SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine aminotransferase), Interpretations
SGPT (Serum Glutamic-Pyruvic Transaminase)
Sample for SGPT (ALT)
- This is done on the serum of the patient.
- The Blood sample can be taken at any time.
- The fasting sample is not necessary.
- Analyze the enzyme on the same day because the enzyme activity is lost at room temperature.
- This enzyme is stable in whole blood for up to 12 to 24 hours; after that time, there is a gradual increase due to release from the RBCs.
- The sample can be stored at 4 °C for 1 to 3 days (ALT is stable when refrigerated).
- ALT, when freezed, shows deterioration.
Precautions for SGPT (ALT)
- Avoid hemolysis because RBC contains increased ALT (SGPT) and AST (SGOT).
- Drugs that may increase the SGPT value are acetaminophen, aminosalicylic acid, ampicillin, allopurinol, cephalosporin, chlorpropamide, clofibrate, cloxacillin, codeine, indomethacin, INH, Methyldopa, methotrexate, nalidixic acid, quinidine, phenylbutazone, phenytoin, salicylates, tetracycline, and propanol.
- Ideally, perform the test as soon as possible or on the same day because the sample’s storage may not be satisfactory.
- Previous I/M injection may increase the level.
Indications for SGPT
- Diagnose liver diseases.
- Monitor liver diseases after the treatment.
- It differentiates jaundice from liver disease or hemolytic anemia.
Definition of ALT (SGPT):
- This enzyme catalyzes the reversible transfer of amino groups between an amino acid, and α-keto acids are called aminotransferase or transaminases.
- One of the aminotransferases is Alanine aminotransferase (ALT), or the old name was glutamate-pyruvate transaminase (SGPT) which will catalyze the reversible transfer of the amino group between an amino acid and α-keto acid where vitamin B6 (pyridoxal phosphate) is the co-factor.
SGPT (ALT) biochemical reaction
Distribution of SGPT (ALT):
- ALT is an enzyme found predominantly in the liver.
- It is distributed in many tissues, with a moderate amount in:
- Kidneys.
- A small amount in:
- Heart, skeletal muscles.
- A minimal amount may be found in the pancreas, spleen, lungs, and RBCs.
Variation of the ALT:
- The day-to-day variation of the ALT is 10% to 30%, and there is diurnal variation.
- ALT is 45% higher in the afternoon than in the early morning.
- Until the age of 15, ALT is higher than the AST; after that, AST is higher than the ALT.
- In a few people, this pattern may reverse after the age of 60.
- Exercise is the major determinant for AST but less for ALT in men.
- Strenuous exercise or bodybuilding increases AST 3-fold and a 50% increase in ALT.
- The effect of the exercise is minimal in the women.
Distribution of SGPT (ALT) in the liver:
- This enzyme is present in cytosolic forms in the liver. The majority of the SGPT is present in the cytoplasm of liver cells.
- There is always a low level of this enzyme in the blood.
- This is a liver-specific enzyme of the transferases.
- The liver hepatocytes contain 3 to 4 times more AST (SGOT) than the ALT (SGPT).
- This is also normally found in bile, CSF, and saliva.
- It is not found in the urine unless there is a kidney lesion.
SGPT distribution in the liver cell
Liver cell injury:
- Any damage to the liver cells, SGPT enzyme, is released, specifically from liver cell necrosis.
- First cytosolic SGPT is released, and in the case of necrosis, then mitochondria SGPT is released into circulation.
SGPT level depends upon the number of liver cells injured
SGPT level depends upon the number of cells injured
- SGPT activity persists longer than the SGOT.
- This enzyme is raised before there are clinical findings of jaundice.
- In viral hepatitis, the SGPT/SGOT ratio is greater than 1.
- Other than the viral cause, the SGPT/SGOT ratio is less than 1.
SGPT (ALT) biochemical reaction and variations in different conditions:
- ALT catalyzes the reaction, and it is reversible.
- Pyridoxal-5‘- phosphate (P-5-P) functions as coenzymes in the amino-transfer reaction.
- The P-5-P is bound to the apoenzyme and serves as a true prosthetic group.
- The P-5-P bound to the apoenzyme accepts the amino group from the first substrate, alanine, to form enzyme-bound pyridoxine-5- phosphate, and the first reaction product is pyruvate.
- This coenzyme increases the ALT activity by 20% in the normal serum.
- Hemolysis increases both AST and ALT because of this enzyme activity in the RBCs compared to serum. This effect is more significant for AST than ALT.
SGPT (ALT) reaction principle
SGPT 1.5 to 8 times (mild or nor elevation) more than the normal level seen in:
- Early, late and subclinical hepatitis.
- Chronic hepatitis.
- Alcoholic hepatitis.
- Alcoholic fatty liver.
- Laennec’s cirrhosis.
- Chemical hepatitis.
- Passive congestion with centrilobular necrosis.
- Rye’s syndrome.
- Cholangitis.
- Hemochromatosis.
- Pancreatitis.
- Granulomatous infections.
- Neoplasia infiltration.
SGPT >8 to 10 times (3 to 10 times than the normal ) more than the normal value seen in:
- Mostly in acute viral hepatitis.
- Chronic active hepatitis.
- Infectious mononucleosis.
SGPT >30 times (20 or more) more than the normal value is seen in:
- Drug toxicity like acetaminophen in alcoholics and malnourished people.
- Viral hepatitis.
SGPT level in various tissue as compared to serum:
- Compared to serum (1 unit) in the heart is 450 times; the liver is 2850 times, the kidney is 1200 times, skeletal muscle is 300 times, the pancreas is 130, the spleen is 80 times, the lung is 45, and RBCs 7 times.
SGPT (ALT) levels in various tissues as compared to the serum (one unit) are:
| Organs | Times more as compared to the normal serum level |
| Liver | 2850 |
| Kidneys | 1200 |
| Heart | 450 |
| Skeletal muscle | 300 |
| Pancreas | 130 |
| Spleen | 80 |
| Lungs | 45 |
| RBCs | 7 |
| Serum | 1 |
AST/ALT ratio:
- The ALT is the cytoplasmic enzyme in the liver, while AST is both a cytoplasmic and mitochondrial enzyme with a wide distribution in various other tissues.
- AST/ALT ratio is typically <1, but infectious hepatitis becomes greater in the liver.
- AST/ALT ratio is usually greater than 1 is seen in:
- The patient with alcoholic liver disease (cirrhosis). AST is more sensitive to alcoholic liver disease.
- Liver congestion.
- Metastatic tumor of the liver.
- AST/ALT ratio of less than 1 is seen in:
- Acute hepatitis.
- Viral hepatitis.
- Infectious mononucleosis.
- The ratio will be less accurate if the AST level is more than 10 times the normal.
| Ratio of enzymes | AST/ALT = <1 | AST/ALT = >1 |
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Diagnostic application of the SGPT (ALT):
- The best indicator for liver cell injury is when both SGPT and SGOT are raised.
- Higher-level are found in hepatocellular disorders than the extrahepatic or intrahepatic obstructive lesions.
- Levels of both enzymes may reach as high as 100 times. 20 to 50 times, the elevated level is frequently found.
- Measuring aminotransferases weekly is useful in hepatitis or other hepatic injuries.
- Because of the accurate measuring techniques, it can detect liver cell injury due to alcohol.
- It is used as a screening test for diagnosing hepatitis due to hepatotropic viruses, especially the hepatitis C virus in blood donors.
- 5 to 10 times the elevation of ALT and AST occurs in the liver’s metastatic carcinoma. AST (SGOT) level is higher than the ALT (SGPT). In the early stages of malignant infiltration of the liver, these enzymes are normal.
- ALT (SGPT) may be raised after intake of alcohol, delirium tremors, and after the administration of the drugs like opiates, salicylates, and ampicillin.
NORMAL SGPT (ALT) level
Source 4
| Age | Male U/L | Female U/L |
| Newborn 12 months | 13 to 45 | 13 to 45 |
| one to 60 years | 10 to 40 | 7 to 35 |
| 60 to 90 years | 13 to 40 | 10 to 28 |
| >90 years | 6 to 38 | 5 to 24 |
Source 2
- Adult / child = 4 to 36 unit/L at 37 °C
- Elderly = slightly higher than the adult
- Infants = Maybe twice high as the adult
Another source
- Men = 10 to 30 units /L (some labs normal is 10 to 40 U/L).
- Women = 9 to 25 units /L (Some labs normal is 10 to 28 U/L).
- Children are two times of adult’s value.
- In children, it is raised because of bone activity, which is normal for children.
- The adult level is achieved by 6 months of age.
- Males are slightly higher than females.
The increased SGPT (ALT) level is seen in:
- Viral hepatitis. There is a markedly increased level.
- Drug-induced hepatitis.
- Chronic hepatitis.
- Infectious mononucleosis.
- Intrahepatic cholestasis.
- Cholecystitis.
- Active cirrhosis.
- Metastatic tumors of the liver.
- Obstructive jaundice.
- Alcoholic cirrhosis.
- The mild increase is seen in :
- Myosotis.
- Pancreatitis.
- Myocardial infarction.
- Shock.
- Infectious mononucleosis.
- Alcohol-acetaminophen syndrome.
- A significant increase in level has been in acute liver diseases.
- A moderately increased level is seen in chronic liver diseases and muscle trauma.
- A mildly increased level is seen in myositis, Myocardial infarction, and infectious mononucleosis.
Acute Viral hepatitis SGPT (ALT) Pattern:
- This rises before the appearance of jaundice.
- The peak level occurs between 7 to 12 days of jaundice.
- Then there is a gradual decrease in the level.
- Normal level after 3 to 4 weeks of the onset of jaundice.
- AST/ALT ratio, which is normally <1, becomes greater > than 1.
SGPT level in Viral hepatitis
Table showing the increase of SGPT in various conditions:
Clinical condition |
The rise in SGPT level with reference to the normal value |
| Viral hepatitis and liver diseases | may reach 100 times |
| Infectious hepatitis | ALT > AST |
| Toxic hepatitis | Extremely high level |
| Infectious mononucleosis | 20 times |
| Intrahepatic cholestasis | maybe raised |
| Extrahepatic cholestasis | Very high level |
| Cirrhosis | 4 to 5 times or higher |
| Metastatic carcinoma | 5 to 10 times |
| Acute myocardial infarction | within normal limits or a very mild increase |
| Progressive muscular dystrophy | May reach 8 times |
| Dermatomyositis | May reach 8 times |
Critical value:
- >9000 U/L seen in Alcohol-acetaminophen syndrome.
This level can distinguish it from alcoholic or viral hepatitis.
Comparison of AST/ALT
- AST (SGOT) is always raised in acute myocardial infarction, where ALT (SGPT) will be normal unless there is damage to the liver.
- ALT (SGPT) is more raised in acute hepatobiliary obstruction than AST (SGOT).
- ALT (SGPT) is more specific than AST (SGOT) for liver cell injury.
- The AST/ALT ratio is higher in alcoholic liver diseases.
- AST (SGOT) is more sensitive to alcoholic liver cell injury.
The main feature of SGPT (ALT) and SGOT (AST):
| Clinical parameters | SGPT (ALT) | SGOT (AST) |
| Normal range | 5 to 35 IU/L | 10 to 40 IU/L |
| Half-life in blood | 35 to 57 hours (3 to 5 days) | 12 to 22 hours |
| Distribution in the body |
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| Location in the liver cells | It is present in the cytoplasm only | It is present in cytoplasm and mitochondria |
| Change with acute inflammatory conditions | It is extremely sensitive | It is moderately sensitive |
| The rise in metastatic or primary neoplasm | It is moderate or no change | It is markedly increased |
| In cirrhosis | It is a mild to moderate increase | It is moderately increase |
| In acute myocardial infarction | It is a mild to moderate increase | It is markedly increase |
Question 1: What is the half-life of SGPT?
Question 2: What is the best indicator of liver cell injury, SGOT or SGPT?
Question 3: Is there any role of RBCs hemolysis in the level of SGPT.
MY SGPT is 88 U/L and SGOT is 63. What kind of prevention should taken by me . I am just 24
You should have a complete Liver function test and viral hepatitis profile. Keep on checking SGPT and SGOT at least every three months.
My son’s test report is SGPT (ALT) 90 plaease tell me how to treat it and what medicine to use
Dear
This SGPT is raised. Please advise complete liver function test with viral profile HBV, HCV. Then best is to consult some good hepatologist or physician.
My SGOT IS 51
SGPT IS 72
What to do
You should have a complete liver function test and hepatitis profile (HBV, and HCV). If these are abnormal then consult the physician.
Good day,
my sgpt is 56 U/L
my sgot is 59 U/L
I’m 34 y/o male. had muscle pain a few days ago due to my new squat exercise routine before taking this test. Is my muscle pain connected with my sgpt sgot levels? should i be worried? thank you
Dear SGOT/SGPT are raised. You should have total bilirubin, direct and indirect, alkaline phosphatase, and gamma GT level. If these are raised then please consult physician for further work-up.
My SGPT 79 & SGOT 48 & GGTP 75
Please suggest
Please advise liver function tests including viral profile and ultrasound abdomen. Consult some good physicians.
My SGPT 79 SGOT 48 GGTP 75
Please suggest
Please advise liver function tests and ultrasound of the abdomen. Consult some good physicians.
My bilirubin 15.5 and sgpt 250 what should I do?
Bilirubin is too high. Please advise the complete liver function test, ultrasound abdomen, and consult a good physician.
My alt sgpt is 10 U/l
Is it normal
Sure it is normal.
Hi i am 24 year old female i have SGOT 52and SGPT 81.5 what should i do. Else every thing in my liver and blood profile is normal.
Please check your hepatitis viral profile. Please rule out any medication. Even aspirin can disturb the LFT.
i m covid patient and my SGPT is 101. and CRP lavel is 0.6 so please suggest what to do
hi
i m covid patient and my sgpt is 101
Please advise complete liver function tests to find any other abnormal values. You definitely need treatment for the Covid. Now, a day’s most doctors are prescribing steroids. Please consult some good physicians.
My sgpt is 110 in liver function test rest is in normal range what it say
Hi my mum 54 years old and her SGPT 52 is it normal.
It is the upper limit. Please advise the complete liver function test.
My sgot is 33 and SGPT 72, is it serious ?
age 32 M
tested in fever 100 F
SGOT is normal, but SGPT is mildly raised which may be due to some medicine like Aspirin. Please repeat after 2 weeks.
My lft result
Liver Function Test. Normal
Bilirubin -Total. : 0.5 mg/dl. 1. 0
Bilirubin – Direct. : 0.2 mg/dl upto 0.4
Bilirubin Indirect. : 0.3 mg/dl 0.2-0.6
SGOT/AST;Aspartate Aminotransferas
: 29 U/L Males : upto 35 U\L
Females : upto 31 U\L
SGPT/ALT;Alanine Aminotransferase
: 34 U/L Males : upto 45 U\L
Femaless : upto 34 U\L
Alkaline Phosphatas. : 78 IU/L
Adults : 18 – 115
Upto 12 yrs : 54 – 369
Total Protein. : 6.4 gm/dL
6 .4 – 8.3 g/dl
Albumin Serum. 3.7 gm/dL
3.5 – 5.5
Globulins. : 2.7 gm/dL 1.8 – 3.4
A/G Ratio. : 1.4:1 2:1
Technology used : Automated procedure On EM 200
I am 51 years
Some values are in boundary
What it indicate
Need more test?
Mostly your tests are in the normal range. I don’t think so. If you have any symptoms then consult a physician and do the tests which he/she thinks are needed.
MY SGPT is 28 U/L and (HBV) DNA is Undetected. What kind of prevention should taken by me . I am just 35
Vaccination for HBV infection is available. I will suggest you get vaccinated.
Hi Dr. Riaz, I am diabetic patient and a stone in my gallbladder with no pain, four months ago SGPT result was 44 U/L , recent test result SGPT is 66 U/L. my age is 41.
I will suggest to control diabetes and get operated on for gall stones. I will suggest consulting the surgeon because gall stones may give rise to a mild increase in liver enzymes.
TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 74.6 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.79 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.25 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.55 mg/dl 0-0.9
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 128.73 U/l < 35
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 90.6 U/l < 45
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 17.5 U/l < 55
PROTEIN – TOTAL PHOTOMETRY 9.05 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 5.2 gm/dl 3.2-4.8
SERUM GLOBULIN PHOTOMETRY 3.85 gm/dL 2.5-3.4
SERUM ALB/GLOBULIN RATIO CALCULATED 1.35 Ratio 0.9 – 2
Please correlate with clinical conditions
Please sugges me what I have to do…..
Is this a indication of liver cerosis
Most tests are normal except for SGOT and SGPT. Please rule out alcohol intake and pain killers.
Hi Sir,
My SGOT – 62.88
SGPT – 132.41
Serum bilirubin – 0.41
Direct – 0.19
Indirect – 0.22
Serum protein – 6.94
Serum Alkaline phosphatase :- 68.86
Albumin – 4.78
Globulin – 2.16
A/G ratio – 2.21
My age 32 .
Is their any thing serious ?
Your SGOT/SGPT is raised, showing liver cell necrosis. Please rule out alcohol and pain killer therapy.
my SGPT is 84 is it to much high ?
I can say this is raised. You should do a complete liver function test. I will suggest repeating your test after 2 to 3 months.
My sister’s SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?
My sisters SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?
These levels are in the normal range; I don’t think is serious. If you are very conscious, repeat liver function tests (LFT) after 2 to 3 months.
hi! my SGPT US 61.45
IM 31 YEARS OLD.
SGPT is slightly raised. You should have done a complete liver function test (LFT).
Sir,
BILIRUBIN-TOTAL 0.30 mg/dL 0.20 – 1.20 Diazonium salt
BILIRUBIN-DIRECT 0.10 mg/dL 0.0-0.3 Spectrophotometric
BILIRUBIN-INDIRECT 0.20 mg/dL 0.0-1.10 Direct measure
ALKALINE PHOSPHATASE 99.00 U/L 38-126 PNP
AST/SGOT 29.0 U/L 17-59 UV with P-5-P
ALT/SGPT 15.0 U/L <35.0 UV with P-5-P
AST:ALT RATIO 1.93 Ratio Upto 1.3 Calculated
PROTEIN, TOTAL 6.80 g/dL 6.3-8.2 Biuret
ALBUMIN 4.10 g/dL 3.5 – 5.0 Bromocresol Green
GLOBULIN 2.70 g/dL 2.0-3.5 Calculated
A/G RATIO 1.52 0.8-1.2 Calculated
AST/ALT ratio and A/G ratio are not normal as per the above. Kindly analyse and advise.
Your LFT values are normal. I may not give importance to calculated values unless the values were abnormal.
FBS 93
HDL 52
LDL 129
VLDL 21
BILIRUBIN 105
SGOT 80
SGPT 92
Kindly analyse and advise
FBS, HDL, VLDL are in the normal range. LDL can be decreased more. Your Liver function tests are abnormal. You must consult a hepatologist.
Sgpt- 47
Sgot- 85
Ratio- 1.5
Bilirubin- 0.4
Your SGPT and SGOT are mildly raised. Please get detailed liver function tests and viral hepatitis profile (HBV, HCV). I hope you are not taking painkillers or alcohol or any other drugs?
My sgot is 51
Sgpt 61
Billirubin 1.8
Blood sugar level 87
TSH 7.5
Ultra sound shows mild fatty liver.
What is your advice?
I feel fatigue
Your SGOT and SGPT are slightly above the normal value. But your TSH (If it is mU/L) level is too high, indicating hypothyroidism. Hypothyroidism can lead to feelings of fatigue. Please read the following link and have a complete workup of thyroid functions.
https://www.labpedia.net/thyroid-part-2-thyroid-stimulating-hormone-tsh-thyrotropin/
SGPT – 102
SGOT – 6
Please advise
SGPT – 102
SGOT – 6
Please advise
SGPT represents a problem in the liver, and SGOT should also need to be raised. This is an unusual picture. I will advise repeating complete liver function tests and viral hepatitis markers as well.
Dr sb i have got my test reports. My sgpt is 139 & Hbv pcr is 892. How is the result dr sb. Waiting for ur kind answer.
SGPT 139 is increased. HBV PCR value needs their normal range. It would be best if you had a physician consultation for the treatment.
TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 61.8 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.78 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.24 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.54 mg/dl 0-0.9
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 19.1 U/l < 38
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 34.4 U/l < 31
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 44.4 U/l < 34
PROTEIN – TOTAL PHOTOMETRY 7.1 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 4.2 gm/dl 3.2-4.8
SERUM ALB/GLOBULIN RATIO CALCULATED 1.45 Ratio 0.9 – 2
SERUM GLOBULIN PHOTOMETRY 2.9 gm/dL 2.5-3.4
Please correlate with clinical conditions.
Method :
ALKP – MODIFIED IFCC METHOD
BILT – VANADATE OXIDATION
BILD – VANADATE OXIDATION
BILI – DERIVED FROM SERUM TOTAL AND DIRECT BILIRUBIN VALUES
GGT – MODIFIED IFCC METHOD
SGOT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
SGPT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
PROT – BIURET METHOD
SALB – ALBUMIN BCG¹METHOD (COLORIMETRIC ASSAY ENDPOINT)
A/GR – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
SEGB – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
Hi Dr. Riaz, Am i suffering from anything serious? Please advice. Thanks
Only your SGOT and SGPT are mildly raised. Rest all tests are normal. I will advise eat more fruits and repeat only these two tests after 2 to 3 months.
Does low uric acid in plasma or serum, an indication of any kidney disorder?
You have not told how low is the blood uric acid level. Please read the following link, and this may be helpful for you.
https://www.labpedia.net/uric-acid-level-blood-uric-acid/
Sgpt -132
Sgot – 98
Alkaline phosphate -242
Bilirubin – 2.1
Your LFT is abnormal and needs a consultation by the physicians.
my sgpt (alt)is 60u/l and sgot (als) is 28 is it normal?
my age is 18 my sgpt(alt)is 60u/l and sgot(ast)is 28 is it risky?
SGPT is slightly raised, but SGOT is normal. Please repeat both tests after one month. Take more fruits during this period. Avoid aspirin.
Sgot is 33.9 and SGPT is 46.2
SGOT looks normal and SGPT slightly above normal. My suggestion is to repeat the LFT (SGPT) after one month.
Hello sir
My wifes sgpt 34 and sgot is 42.she is 7 months preganant.. Also she is taki g aspirin as per doctors advice..is thia range is normal?
Also the d dimer is 841..
These values are normal. Because the aspirin may increase SGOT, when she stops aspirin, I hope SGOT will also be below 40. Give her more fruits that may help her.
What about d dimer sir..
Please see the following link for D-dimer.
https://www.labpedia.net/d-dimer-test-fragment-d-dimer/
What about d dimer sir?
my SGPT is 87.77 and my SGOT is 92.47 what should i do? thank u
Your LFT is abnormal; you need further workup like complete LFT with gamma-GT. Ultrasound of abdomen. If you are using alcohol, first quit and recheck LFT after one month.
If no improvement, then consult a hepatologist or gastroenterologist.
Sir my LFT test is
SPGT LEVEL 199
SOGT LEVEL 65
BILUBRIN LEVEL 0.80
IS IT IN DANGEROUS LEVEL
Your liver function tests (LFT) are abnormal. No doubt, bilirubin is normal. This needs to rule out liver cell necrosis like alcohol intake, viral hepatitis, and some drug use.
It would be best if you had thorough work up to find the cause of abnormal LFT.
HDL / LDL Cholesterol Ratio
Value: 0.50 ratio
Normal Range:-ratio – -ratio
SGOT/AST
Value: 54.00 U/L
Normal Range:0U/L – 50U/L
SGPT/ALT
Value: 92.20 U/L
Normal Range:0U/L – 50U/L
GGTP (Gamma GT)
Value: 71.00 U/L
Normal Range:0U/L – 55U/L
SGOT/SGPT Ratio
Value: 0.59 ratio
Normal Range:0.7ratio – 1.4ratio
Proteins, Serum
Value: 7.26 g/dL
Normal Range:6.6g/dL – 8.3g/dL
Albumin, Serum
Value: 4.65 g/dL
Normal Range:3.5g/dL – 5.2g/dL
A/G Ratio
Value: 1.78 ratio
Normal Range:1.2ratio – 2.2ratio
Bilirubin Total, Serum
Value: 1.07 mg/dL
Normal Range:0.3mg/dL – 1.2mg/dL
Bilirubin Direct, Serum
Value: 0.20 mg/dL
Normal Range:0.0mg/dL – 0.2mg/dL
Bilirubin- Indirect, serum
Value: 0.87 mg/dL
Normal Range:0.1mg/dL – 1.0mg/dL
Alkaline Phosphatase, Serum
Value: 109.00 U/L
Normal Range:30U/L – 120U/L
please suggest. Is it critical?
Your SGOT, SGPT. and Gamma GT is raised. It would help if you had further workup to rule out any disease of the liver. Please consult the physician for further workup.
Hi I’m George ALT/SGPT 14.08 U/L 14.08 ukat/L, please help me understand my findings. Thank you and Godbless
SGPT 14.08 U/L is in the normal range, and no need to worry.
Thank you so much Dr. Riaz
You ease my worries. Thank you for helping me.
More power and Godbless
im 35 year old my last week report about sgpt leve is 77
and bilirubin leve is 0.37
every week i did my test and some time result shown sgpt level 80 then 60 then 65 then 35 then 55 then 89 then 77 and bilirubin leve is always normal. whats i do is this thing is dangerous or not
SGPT level fluctuations mean that some minor injury in the liver, the causes may be viral hepatitis C, alcohol intake, some pain killer medications. You have to rule out these possibilities.
Thanks for the replay dear , few month ago i was sick and i used antibiotics medicines for 20days, after that is issue is rise ( increase of sgpt) i don’t use alcohol..
i used using the Estar tablet 10mg twice in a week, is this tablet is harmful in high SGPT or not please answer on this,,, and today on 5//9/2021 i repeat my sgpt test that was 61 befor is that was 77 in last week,,, i try to control this on proper diets,, actually im food lover and i like to eat fish and meals but now a days im on diet,, is this problem can be handle on diet or i need to visit doctor
thanks again for your replay to my message Doctor
Your LFT is definitely abnormal. I will suggest consulting some hepatologist or gastroenterologist.
Thanks
yes i have ulcer problem from last 7 year …i just want to know that ,can i use Estar tablet 10mg , because if i dont use this tablet then i feel bad
I think you can use Estar. For more details, see this link.
https://www.webmd.com/drugs/2/drug-10716/estar-topical/details#:~:text=This%20medication%20is%20used%20on,the%20growth%20of%20skin%20cells.
I will see the link sir .. and thanks for your help I will remember you in my prayers
SGPT/ALT is 9 and SGOT/AST is 11. The SGPT/ALT is very low. What does it mean? I am 50.
I will say that these tests are normal and no need to worry.
my SGOT 36.0 U/L AND SGPT 42.6 U/L Please advice
SGOT is normal, and SGPT is boerder-line. Please take more fruits and repeat the liver function test after one month and then let me know the result.
Sgot 43
Sgpt 50
Should I worry?
Age 25
Your SGOT/SGPT are mildly raised. You need to worry and find the cause like viral hepatitis, and some drugs may increase. Better consult a physician to find the cause.
Sgot 47
Sgpt 88
S Bilurubin total 1.0
ALP 170
RFT all normal values
Blood sugar 70
Should I worry?
Age 36
Was taking 2-3 drinks daily from last 20-25 days
I think your SGOT/SGPT is raised due to alcohol intake. I will suggest stopping alcohol for at least 2 to 3 months till these enzymes are normal. Then you can take off and on alcohol but not regularly. Otherwise, you will develop cirrhosis of the liver, which ultimately leads to liver failure.
Dear Dr. Diaz
I wonder why AST is specifically more elevated in case of periportal necrosis in Preeclampsia ?
Best, regards
Rivaldo
You may see hypertension, proteinuria, oliguria, pulmonary edema, thrombocytopenia, and elevated transaminase level in preeclampsia. I think these are the complications of preeclampsia.
my sister’s sgpt test’ report says that she has 186 U/L. is it too much? what we can do for her? she is only 9 years old.
What is SGOT, total bilirubin and alkaline phosphatse? Please also ask for viral markers (HBV. HCV).
BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl
LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)
I don’t know your age. All your parameters are normal except SGOT/SGPT, Which indicates liver cell injury. I hope you are not taking alcohol. Would you please check your viral hepatitis profile (HBV, HCV)?
36 age sir
My age 36, I consume alcohol daily, What should I do Sir ?
BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl
LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP ) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)
I’m 26 female and my SGPT is 43.4 rest everything is normal
Also creatinine serum is 0.86
Do I need to worry and wha further tests should be done?
I don’t think you need to worry. Just repeat SGPT after 2 to 3 months.
Sgpt-1200 u/ml
Sgot-400 u/ml
Billirubin is 4.2
My age is 49 .. What to do?
Your liver function tests are abnormal, and you must have clinical jaundice. You should check your viral profile like HBV, HCV, and HAV.
Doctor, sgpt and sgot is in u/lit
my sgpt is 31u/l and i’m a 20 yr old female . is it high?
What about SGOT?. But this is in the normal range.
MY DR. JUST ASKED ME TO GET THAT SGPT TEST DONE ALONG WITH THYRIOD. WHEN MY SGPT RESULTS WERE OUT THEY SAID IN FEMALES IT HAS TO BE 21U/L AND BELOW AND ACCORDINGLY MY LEVELS ARE HIGH. PRETTY CONFUSED AS MY REPORT INDICATES NORMAL WHERE AS DR. SAYS ITS NOT, AND THEN THEY ASKED ME TO DO FIBRO SCAN SAYING I MIGHT HAVE A FATTY LIVER AND AFTER DOING THAT MY RESULT WAS NORMAL.
My SGOT is 47 and SGPT is 16. I am 22 years old female. I have lost my appetite and doesn’t feel hungry at all.
SGOT is the upper limit of normal. I will advise you to repeat the complete liver function test and ESR after at least 1 to 2 months. Meanwhile, avoid aspirin intake. Are you taking any other medications?
Sir my LFT(6 para) test is
Serum bilirubin is 6.5 total
Serum bilirubin is 4.5 direct
Serum bilirubin is 2.0 indirect
Sgpt(AlT) is 1957
Alkaline phosphate is 259
Gamma GT is 44
Sir it can be normal my niece age is 18 years
These liver function tests are abnormal, indicating hepatitis. Have you done viral profiles like HBV and HCV? She needs consultation to find the cause of jaundice.
Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause and what to prevent. Please guide.
Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause and what to prevent. Please guide.
Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause and what to prevent. Please guide.
Your SGPT is raised, which indicates liver cell injury.
Fasting glucose level is in the normal range. Cholesterol is also not high.
You need a thorough workup for the liver. I hope you are not taking any painkillers?
Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause and what to prevent. Please guide me.
Regards
Your fasting glucose favor diabetes mellitus, so you should rule out diabetes mellitus. Please check fasting glucose level at least three times, and if still, it is more than 126 mg/dL, then it is diabetes mellitus.
Your cholesterol level is raised.
It would be best if you had a physical checkup to rule out Diabetes mellitus.
Also, it would be best if you had diet control for cholesterol.
Hi DOCTOR, I RECENTLY DID MY LFT AND RESULTS ARE SGOT 56.4, SGPT 54.7, DIRECT AND INDIRECT BILLIRUBIN SKIGHTLY INCREASED,
I HAVE GILBERT’S SYNDROME ALSO I DID MY SONOGRAPHY, EVERYTHING WAS NORMAL. EXCEPT SLUDGE IN GALL BLADDER, WHAT SHOULD I DO?
This is a benign condition and there is no specific treatment. Gilbert’s syndrome is a life-long disorder.
You have to avoid some of the drugs. here are a few of those.
1. Gemfibrozil, for lowering cholesterol.
2. Statins, also used for reducing cholesterol, when taken with gemfibrozil.
Please see this links:
https://labpedia.net/gilberts-syndrome-diagnosis/
Sir I am 28 years old female my SGPT IS 49
Alkaline phosphate is 102, GGTP is 15 are my reports normal sir??
These values are normal except for SGPT, which is the normal upper range. You can repeat SGPT, SGOT after 2 to 3 months.
My sgpt is 165 I am 34 years old
Your SGPT is raised, indicating liver cell injury. Would you mind letting me know complete liver function tests and Ultrasound abdomen report?
Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
VSG: 22 mm/hr
Liver Profile:
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
Liver Profile:
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
Your tests are normal, except GGT and SGPT are normal upper range. This may be due to pain killer intake or any other medicines. I will suggest you, please repeat after 2 to 3 months only GGT, SGOT, and SGPT.
Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L
My CBC report:
Platelete count is 89000
Lymphocytes 51%
MCH 25.88%
LFT test Reports
Only SGPT is raised upto 38 IU/L all other Reports are normal… Plz suggest what to do next
Platelets are low; lymphocytes are more than the normal range. SGPT and MCH is normal. This patient needs workup. Why are platelets low?
My LFT report:- Impression (Grade 1 fatty liver)
SGOT:- 35 IU/L
SGPT:- 71IU/L
Bilirubin Total:- 2.6 mg/dl
Bilirubin Direct:- 1.3 mg/dl
Bilirubin indirect:- 1.3mg/dl
In every test, I have noticed my bilirubin level has been elevated what is the reason behind it. I have consulted a few doctors but they have not been able to find the reason behind it.
Your case fits into Dubin-johnson syndrome, but your SGPT level does not favor it.
https://labpedia.net/dubin-johnson-syndrome-diagnosis/
See above link.
I hope you are not a drinker. Bilirubin above 2 mg/dL will show yellowness of the eyes. Would you please check your hemoglobin, viral hepatitis profile, and urine examination?
Then let me know the results.
My complete report as follows
LIVER & KIDNEY PANEL, SERUM
(Reflectance Photometry,Direct ISE)
Bilirubin Total 0.60 mg/dL 0.30 – 1.20
Bilirubin Direct 0.11 mg/dL <0.30
Bilirubin Indirect 0.49 mg/dL <1.10
AST (SGOT) 37 U/L <50
ALT (SGPT) 80 U/L <50
GGTP 71 U/L <55
Alkaline Phosphatase (ALP) 108 U/L 30 – 120
Total Protein 6.73 g/dL 6.40 – 8.30
Albumin 4.20 g/dL 3.50 – 5.20
A : G Ratio 1.66 0.90 – 2.00
Urea 21.73 mg/dL 17.00 – 43.00
Creatinine 0.82 mg/dL 0.67 – 1.17
Uric Acid 7.43 mg/dL 3.50 – 7.20
Calcium, Total 8.89 mg/dL 8.80 – 10.60
Phosphorus 3.48 mg/dL 2.40 – 4.40
Sodium 138.70 mEq/L 136.00 – 146.00
Potassium 4.11 mEq/L 3.50 – 5.10
Chloride 104.14 mEq/L 101.00 – 109.00
These test has done on morning and last night I had alcohol… does it may refect in test
Kindly tell me what to do
Definitely, alcohol will affect SGOt/SGPT and GGT levels. Your cholesterol level is also normal upper limit (borderline case). You have not mentioned the HDL.
LDL and VLDL are atherogenic and predispose to heart diseases. I will suggest quitting alcohol, and it will damage the liver.
Test Name Results Units Bio. Ref. Interval
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130
In addition
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130
Test Name Results Units Bio. Ref. Interval
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130
My sisters SGPT level is 2080 and 0-35 is recommended in report. How bad it is??
Bilirubin 2.6
RBC count 5.35
Any suggestions
SGPT level and bilirubin are raised. There is liver cell injury. Would you please advise liver functions test and viral hepatitis profiles?
Sgpt 46
Direct bilirubin 0.6
Others normal
Should I worry or continue eating everything?
I’m not alcoholic.
I have gastritis for 2 weeks also
Bilirubin level is normal. For gastritis, you need treatment. At least avoid spices.
Can gastritis be cured without medicines by dietary changes sir?
Hi doc my sgpt is 287 but other than that all my test are normal
My doc ask me to undergo liver ultrasound and these is what it says:
The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated
Hi doc, my sgpt level is 287, so my doctor said to undergo liver ultra sound and this is my ultra sound says
The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated
And another thing doc, i read in the internet that they need 5ml of blood for sgpt test
The clinic i went only got 1ml of my blood
SGPT is raised, you need a complete liver function test including gamma GT. 5 mL blood is ideal, but someone may get enough serum from one mL. Your SGPT indicates liver cell injury.
Thank u doc, another thing doc
All my test are normal, only my sgpt is high
Thanks again doc.
Is SGPT 56, SGOT 29 normal? Took flagyl and librax for some days.
THank you in advance (man)
SGPT is raised (abnormal), but SGOT is in the normal range. SGPT indicates liver cell injury. When SGPT is raised, there should be a mild increase in the SGOT, which is not in your case. Better check both parameters after one month.
My name is Mehedi hasan. My test result from LABAID
HBsAg=Positive sample OD >10000 Cut-Off OD 1.0
Bilirubin=1.1 mg/dl
ALT(SGPT)=51 U/L
AST(SGOT)= 32 U/L
HBeAg= Negative
Anti-HCV= Negative
Anti-HBe= Positive sample OD 400 Cut-Off OD 100
These findings of HBsAg and HBeAg indicate chronicity. Your SGPT is mildly raised, but SGOT is normal. I will suggest keeping an eye on liver function tests or getting the treatment for the hepatitis B virus.
Usually both ast and alt are high in hepatic metastasis?
In metastatic, infiltrate of carcinoma depends upon the involvement of the liver area. There may be raised AST/ALT and alkaline phosphatase levels.
Sgot – 43 and Sgpt – 48 my age is 36 I need to consult doctor.
Sgot – 43 and Sgpt – 48 my age is 36. Could I need to consult doctor.
You need to repeat complete liver function tests after 2 to 3 months, and then let me know the results.
Bilirubin(total) – 0.59 mg/dl
Bilirubin(direct) – 0.15 mg/dl
Bilirubin (indirect) – 0.44 mg/dl
Sgot -52 iu/l
Sgpt – 135 iu/l
Alkaline phosphatase – 168 u/l
Total protein – 7.6 gm/dl
Albumin – 5.5 gm/dl
Globulin – 3.1 gm/dl
A/G ratio – 1.5
Ggt – 34 iu/l
Age – 22 , No smoke and drinking.
Pain in upper abdomen liver side
Emergency?
Your SGOT and SGPT are raised, indicating liver cell injury. Would you please rule out any use of drugs? Also, check your viral profile (HBV, HCV).
No drug
Liver Function Test (LFT)
Serum Bilirubin, (Total)
Method: Diazo
1.06 mg/dl 0.2-1.2
Serum Bilirubin, (Direct)
Method: Diazo
0.34 mg/dl 0.0 – 0.5
Serum Bilirubin, (Indirect)
Method: Calculated
0.72 mg/dl 0.0 – 0.8
Aspartate Aminotransferase (AST/SGOT)
Method: IFCC
40.85 U/L 5 – 34
Alanine Aminotransferase (ALT/SGPT)
Method: IFCC
68.00 U/L 0 – 55
Alkaline Phosphatase (ALP)
Method: IFCC AMP Buffer
96.00 U/L 43 – 115
Gamma Glutamyl Transferase (GGT)
Method: IFCC
38.5 U/L 12-64
Serum Total Protein
Method: Biuret
8.22 g/dl 6.6 – 8.3
Serum Albumin
Method: Bromo Cresol Green(BCG)
5.01 g/dl 3.5 – 5.2
Serum Globulin
Method: Calculated
3.21 gm/dl 3.0 – 4.2
Albumin/Globulin Ratio
Method: Calculated
1.56 Ratio 1.2 – 2.5
SGOT/SGPT Ratio
Method: Calculated
0.60 Ratio 0.7 – 1.4
My age is 23. Is there anything need to worry.
Your SGOT and SGPT are mildly raised. Please repeat SGPT/SGOT after 2 to 3 months. Also, check your HBV and HCV status. I hope you are not taking any medicines?.
15 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and skipping breakfast. can this may be the reason?
15 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and skipping breakfast. can this may be the reason?
hi…sir 5 day before sgpt test 45iu/l sgot 31iu/l but now today sgpt 576.8 sgot 509u/L I hv jaundice what happen sir….plz suggest
It means your liver function tests are abnormal. Would you please advise viral markers (HBV, HCV, and HAV)?
My sgpt is 110 in liver function test rest is in normal range what it say
Raised SGPT indicates liver cell injury. It needs a thorough workup to find the cause.
MY SGOT IS 331 OR SGPT IS 171 PLS SOME ADVISE
SGOT/SGPT raised level indicates liver cell injury. You should have viral markers and have ultrasound abdomen. Please keep on checking the liver function tests every three months at least.
SGOT-39
SGPT-66
Drinks occassionally. Is it high? I have gilberts syndrome and little bit high cholestrol
Age-30
SGPT is raised, and it indicates liver cell injury. Can you check your gamma GT level? If it is raised, then avoid alcohol.
Ultrasound abdomen is normal
Hello Doctor,
I went through with the routine checkup and Below are my reports.
Please advise.
HbA1c 5.7
LDL CHOLESTEROL – DIRECT 173
TOTAL CHOLESTEROL 239
HDL CHOLESTEROL – DIRECT 37
LDL / HDL RATIO 4.7
TC/ HDL CHOLESTEROL RATIO 6.5
BILIRUBIN – TOTAL 1.49
ASPARTATE AMINOTRANSFERASE (SGOT ) 207.9
ALANINE TRANSAMINASE (SGPT) 395.76
Your reports are not good. It looks you are not living a healthy life. Your HDL is low, good cholesterol, while LDL is high, which is bad cholesterol. Liver enzymes are raised. Please consult a physician to find the cause of these abnormalities.
Hi Doc! My SGPT is 358.1 and alkaline is 135.7 Before My test , Im having really bad abdominal pain in the center . What to do ?
Your SGPT is raised while alkaline phosphatase is in a normal range. I will suggest complete liver function tests and viral markers. You have not mentioned the age.
Sir my sgot-22.7,sgpt-38, alkaline phospa te-58,total protein-7.83, total cholesterol-199,ldl-141,hdl-53, triglycerides-118, please advise
You have not mentioned your age. Your lipid profile looks good. Only cholesterol is the upper limit.
39 year old male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?
Thank you
39 year old Male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?
Congratulations, your LFT is normal.
MY AST (SGOT) is 58
MY ALT (SGPT) is 115
I am 63 year old female
Your liver functions are abnormal. What about total bilirubin?. I will suggest doing complete liver function tests. I hope you are not taking alcohol?. Your enzymes indicate liver cell injury. It needs full workup and consultation with the physician.
My sgpt is 124 sgot 165 and ggt 65
Is it serious sir ?
Both enzymes are raised. Not good for your health. Please consult some gastroenterologist and have complete work up. Health is wealth.
Hi Dr. Riaz,
I drink 3 times a week heavy (270ml in one sitting) from last 10 years. I have been reading on LFT and so did the test.
My SGOT is 38 (0<30) and SGPT is 95 (0<45) rest stuff are all under normal range.
Can you please advice me further diagnosis.
PS: I am healthy and fit and heavily cut on my drink from last few weeks (sitting once in a week 180-240 ml)
Raised SGPT level indicates liver cell injury. SGOT is not specific for liver cell injury as compared to SGPT. I suggest that you quit the alcohol and repeat the liver function test after 3 months. Otherwise, you may develop liver cirrhosis.
Hii sir
My bilirubin total 1.42
Sgot 65.14
Sgpt 76.48
I am 21 y old
Your SGOT and SGPT are raised, indicating liver cell injury. I hope you are not taking alcohol?. If not then go for hepatic viral profile.
Hi Doctor
6 months back I have done full body check up and I have found my Sgpt -150 ,sgot-72 then I did test for hepatitis B&C and it also came negative and then I farther proceed with ultrasound and it came as grade 2 fatty liver and size of the liver was 17.2 .
By that time I was 30 ,hight 164 cm and weight 81 kg.
I controlled my food habits and did regular exercise and now it is showing after 6 months sgpt-72,sgot-48 and other parameters are ok.
How long it will take to come back to normal or any thing to concern and do I need to go for fibro scan
If liver cells are insulted by alcohol or anything else, it will take at least 3 months to regenerate. Also, try to take more fruits. In your case, it is 6 months, and still, SGPT is raised, indicating liver cell injury. If it remains elevated, then consult a gastroenterologist (or hepatologist).
Forgot to mention my weight is 62 now
My daughter is 2.5 years old today she felt pain in stomach when I done her sgpt it’s too high 450 now what I please guide me
Which doctor I need to consult .
You should have complete liver function tests (LFT) and an ultrasound abdomen. After workup, consult a pediatrician.
hi Dr Riaz,
Could you please comment on this.
Test Name Results Biological Reference
Interval Units Specimen Test Method
SGOT (AST) 32.15 < 35 U/L Serum IFCC without P5P
SGPT (ALT) 53.58 H < 45 U/L Serum IFCC without P5P
Gamma GT (GGT) 39.00 < 55 U/L Serum Enzymatic,Colorimetric
Assay
Uric Acid 7.95 H 3.5 – 7.2 mg/dL Serum Enzymatic Colorimetric
Method
In your lab tests, SGPT is slightly raised, and uric acid is also. You need to repeat SGPT/SGOT and uric acid after at least 1 to 3 months. If still raised, you will need medicine for uric acid and a detailed workup for liver function.
Thank you Doc. Appreciate so much
My wife is 37 weeks and 2 days pregnant. She had severe itching problem but now it’s resolved. LFT level on 14.02.2022 SGPT 226 ,SGOT 149, ALP 188 ,GT 44 all others are in normal range. Fasting bile acid test (4.5 umol/l) with in normal range. no symptom of jiaundice. no other symptoms. HAV IgM non reactive, HAV IGg reactive, anti HEV IGg and IgM non reactive, HbsAg non reactive and anti Hcv non reactive. PT 10 sec., APTT, 25 sec.,.INR 0.91. Abdominal ultrasound showed liver has mildly increased echogenicity. After some dietry change and taking hepa merz syrup for 10 days. Repeat LFT on 24.02.2022, the SGPT 77, SGOT 36 and ALP 176 all other are in normal range. Up till now, according to USG, dilivery is normal. I already consulted two gynecologists, one,s advice is normal dilivery and other in favor of inducing dilivery at 38 week due risk of baby stillbirth. With these elevated liver enzyme, can we go for normal dilivery or should induce dilivery at 38 weeks. Suggest some advice.
A gynecologist will give a better answer. Your lab reports say that she has hepatitis A infection and is in recovery. Hepatitis E infection is dangerous in pregnancy, but that test is negative. I will suggest That you consult the third gynecologist and see what she says.
Thank you sir for your quick response. On the basis of these level of elevated enzyme, can we diagonse inertahepatic cholestasis or Acute fatty liver disease?
Please see this link; this may be of help.
https://labpedia.net/alkaline-phosphatase-level-alp/
Also, you can see this link for acute fatty liver in pregnancy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538964/
Bonsoir Dr Riaz s’il vous plait j’ai besoin de explications :
Asat/got <40ul/L
Alat/gpt <37ul/L
ALTL 5.5u /L
ASTL 11.7u/L
Crej2 65.7umol/L
Urée 0,5-7,5mmol/L
Créatinine 40-120umol/L
GOT/GPT is normal, indicating liver function. Urea/Creatinine gives information about kidney function, which is also in the normal range.
Votre SGPT/SGOT, l’urée et la créatinine sont dans la plage normale. Ces tests parlent des fonctions hépatiques et rénales
SGPT 77
SGOT 30
Currently taking Isotretinoin. Is the mild increase in SGPT caused by Isoretinoin?
SGOT 30
SGPT 77
Currently taking Isotretinoin. Is the mild increase caused by Isotretinoin?
This medicine is causing damage to your liver that leads to an increase in SGPT level. You can stop this medicine and repeat SGPT/SGOT after 1 to 2 months.
My test result shows SGPT(ALT) 115 IU/L
ALKALINE PHOSPHATASE 44.5 IU/L
GAMMA GT 51 IU/L
Please help interpret
SGPT is raised, and Gamma GT is a very mild increase. It indicates liver cell injury. This may be due to some drugs, alcohol, or viral hepatitis. It would be good to check your liver function tests (LFT) and hepatic viral profile.
Why should you not use hemolyzed serum for ALT determination?
Because RBCs are also the source of ALT.
I am 43 years old Male my
SGPT is 43
SGOT 23
Kindly advise if there is something to worry about? thank you very much…
SGPT is the normal upper limit, and SGOT is normal. I will suggest repeating the test after one month and taking more fruits. At this stage no need to worry.
Thank you very much Dr. Riyaz… more power to you…
Thanks.
Hello Dr. Sb,
I am 42 years and my SGPT is 154 . what does it indicate?
SGPT is raised, indicating liver cell injury. This is not good for health. Please advise complete liver function test and viral markers (HBV, HCV). It would be better to consult a physician.
Sir my LFT(6 para) test is
Serum bilirubin is 6.5 total
Serum bilirubin is 4.5 direct
Serum bilirubin is 2.0 indirect
Sgpt(AlT) is 1957
Alkaline phosphate is 259
Gamma GT is 44
Sir it can be normal my niece age is 18 years
Hello Dr. Riaz ,
Below are my details is there a issue in liver and is it concerning ?
BILIRUBIN – TOTAL 0.6 mg/dl
BILIRUBIN -DIRECT 0.2 mg/dl
BILIRUBIN (INDIRECT) 0.4 mg/dl
ASPARTATE AMINOTRANSFERASE (SGOT ) 42 U/l
ALANINE TRANSAMINASE (SGPT) 90 U/l
ALKALINE PHOSPHATASE 76 U/L
GAMMA GLUTAMYL TRANSFERASE (GGT) 60 U/l
PROTEIN – TOTAL 7.1 gm/dl
ALBUMIN – SERUM 4.9 gm/dl
SERUM GLOBULIN 2.2 gm/dL
SERUM ALB/GLOBULIN RATIO 2.23
My age is 34
SGPT and GGT are raised, indicating liver cell injury. I hope you are not taking any form of alcohol or pain killer?. You need to consult a physician.
My age is 34
I am 39 years old Female
My SGOT is 213.4 I am currently taking medications and supplements for my liver. After 2 weeks I took another lab exam for my SGOT and SGPT.
Right now my SGOT is 37.2 but my SGPT is high 54.4
What was the SGPT the first time that you have not mentioned it? if you repeat the test after two weeks, SGPT may become normal by then?.
Age-36
Female
SGPT -75
USG report normal
How can I decrease the SGPT level?
Is it serious?
Please suggest some foods help to reduce SGPT.
walking can help?
I’m 36 years old female
SGPT 75
What I can do to decrease the sgpt?
Please suggest some foods help to reduce SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.
I’m 36 years old female
SGPT 75
USG report is normal
What I can do to decrease the sgpt?
Please suggest some food help to decrease the SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.
This SGPT may be due to medication. If you can afford it, stop this medication for one month and recheck the SGPT. As regards fruits, you can try grapefruit.
Sir my age is 22. I do not consume alcohol
Total bilirubin=3.9
Direct bilirubin = 0.5
SGOT = 106
SGPT = 406
ALP P = 139
I consulted a doctor he advised that it is viral hepatitis with low virulence, no medication is needed. It will get good automatically. Do i need to worry
Please get a viral hepatitis profile (HBV, HCV, HAV). No doubt there is an insult to the liver.
Please advise viral hepatitis profile (HBV, HCV, HAV). Your LFT shows insult to the liver.
Hi
My mother’s Sgot is 16 and Sgot is 6.30, though the values are within the normal range but the Sgot/Sgot ratio is 2.54. Is it a cause of concern? Please advise
When SGOT and SGPT are normal, then no need to see the ratio.
Sir, my SGPT – 98, SGOT- 70 All the other values in my liver function test are in normal range. Platelet count is 328 and fasting Glucose is 92. My Lipid profile is also in normal range. Please advice next step
Your SGOT/SGPT is raised, indicating liver cell injury. It would help if you had worked up, and I hope you are non-alcoholic. Please check your hepatitis viral profile.
sir my mother is 42 and her LFT profile is
BILIRUBIN – TOTAL 0.61 mg/dl
BILIRUBIN -DIRECT 0.18 mg/dl
BILIRUBIN (INDIRECT) 0.43 mg/dl
SGOT – 36 U/l
SGPT-43 U/l
ALKALINE PHOSPHATASE -81U/L
PROTEIN – TOTAL 7.30 g/dl
ALBUMIN – SERUM -4.2 g/dl
SERUM GLOBULIN -3.10 g/dL
and Lipid profile is –
Total cholesterol-192 mg/dl
Triglyceride- 169 mg/dl
HDL- 50 mg/dl
VLDL- 33.8 mg/dl
LDL- 108.2
Non-Hdl-142
LDL/HDL RATIO- 2.16 %
TOTAL/HDL RATIO – 3.84
please advice is there any thing to worry?
There is no worry about these results only if you can control her cholesterol, triglycerides, and LDL. While HDL is good. Please manage the fat intake and advise exercise.
Hi.
I did test 2 weeks ago for my job alplication. My sgpt is 51, and sgot 38.
So i need to get some medicine and retake the test. And now my sgpt is 34 and sgot same 38.
Can you please explain what happened to me 2 weeks ago? Im so curious
Thanks
SGPT mild raise may be due to intake of pain killers even. So that might be due to some drugs effect. After a few days liver becomes normal.
Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!
Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!
Raised SGPT indicates liver cell injury. Please check your viral profile (HBV, HCV, HAV). Are you taking any medicine or alcohol?
Grapefruit is considered good for the liver.
BILIRUBIN, TOTAL 1.01
BILIRUBIN CONJUGATED (DIRECT) 0.36
BILIRUBIN (INDIRECT) 0.65
ALANINE AMINOTRANSFERASE(ALT/SGPT) 63
ASPARTATE AMINOTRANSFERASE(AST/SGOT) 44
ALKALINE PHOSPHATASE 72
PROTEIN, TOTAL 7
ALBUMIN 4.6
A/G RATIO 1.92
Is this normal?
My age is 29, Do I need to worry?
Your SGPT/SGOT level is mildly raised, indicating liver cell injury. It would be best if you found the cause of liver cell injury. Please check your viral hepatic profile in case of non-alcoholics.
Doctor, my husband’s LFT report as follows. Total protein 7.1g/dl
Albumin 4.5 g/dl
Globulin 2.6
Albumin globulin ratio 1.73
Bilirubin total 1.06
AST/SGOT 20.2
ALT/ SGPT 27.6
ALKALINE PHOSPHATASE 85
GGT 70.3
He is 40 years old and over weight. now he follows a diet plan. His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.
GGT is not too high. It is an indicator of alcohol intake. I hope he is a non-smoker and non-alcoholic. You can repeat GGT after 1 to 2 months. Let him reduce his weight. If possible, ask him to take more fruits.
No doctor. He is non alcoholic and non smoker. But he has blood sugar, pressure and cholesterol. Take medications for that. All values are within reference range. Thank you for your advice.