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SGPT (Serum Glutamic-Pyruvic Transaminase), ALT (Alanine aminotransferase), Interpretations

November 3, 2024Chemical pathologyLab Tests

SGPT (Serum Glutamic-Pyruvic Transaminase)

What sample is needed for SGPT (Serum Glutamic-Pyruvic Transaminase)?

  1. This is done on the patient’s serum.
  2. The Blood sample can be taken at any time.
  3. The fasting sample is not necessary.
  4. Analyze the enzyme on the same day because the enzyme activity is lost at room temperature.
  5. This enzyme is stable in whole blood for up to 12 to 24 hours; after that time, there is a gradual increase due to release from the RBCs.
  6. The sample can be stored at 4 °C for 1 to 3 days (ALT is stable when refrigerated).
    1. ALT, when freezed, shows deterioration.

What are the precautions for SGPT (Serum Glutamic-Pyruvic Transaminase)?

  1. Avoid hemolysis because RBC contains increased ALT (SGPT) and AST (SGOT).
  2. Drugs that may increase the SGPT value are acetaminophen, aminosalicylic acid, ampicillin, allopurinol, cephalosporin, chlorpropamide, clofibrate, cloxacillin, codeine, indomethacin, INH, Methyldopa, methotrexate, nalidixic acid, quinidine, phenylbutazone, phenytoin, salicylates, tetracycline, and propanol.
  3. Ideally, the test should be performed as soon as possible or on the same day because the sample’s storage may not be satisfactory.
  4. Previous I/M injections may increase the level.

What are the indications for SGPT (Serum Glutamic-Pyruvic Transaminase)?

  1. Diagnose liver diseases.
  2. Monitor liver diseases after the treatment.
  3. It differentiates jaundice from liver disease or hemolytic anemia.

How will you define SGPT (Serum Glutamic-Pyruvic Transaminase)?

  1. This enzyme catalyzes the reversible transfer of amino groups between an amino acid, and α-keto acids are called aminotransferase or transaminases.
  2. One of the aminotransferases is Alanine aminotransferase (ALT), or the old name was glutamate-pyruvate transaminase (SGPT), which will catalyze the reversible transfer of the amino group between an amino acid and α-keto acid where vitamin B6 (pyridoxal phosphate) is the co-factor.
    SGPT (ALT) biochemical reaction

    SGPT (ALT) biochemical reaction

What is the distribution of SGPT (ALT) in the body?

  1. SGPT (ALT) is an enzyme found predominantly in the liver.
  2. It is distributed in many tissues, with a moderate amount in:
    1. Kidneys.
    2. A small amount in:
      1.  Heart, skeletal muscles.
  3. A minimal amount may be found in the pancreas, spleen, lungs, and RBCs.

What is the variation of the SGPT (ALT) during the day?

  1. The SGPT (ALT) varies from 10% to 30% daily and has a diurnal variation.
  2. SGPT (ALT) is 45% higher in the afternoon than early morning.
  3. Until the age of 15, SGPT (ALT) is higher than SGOT (AST); after that, SGOT (AST) is higher than SGPT (ALT).
  4. In a few people, this pattern may reverse after 60.
  5. Exercise is the major determinant for AST but less for ALT in men.
    1. Strenuous exercise or bodybuilding increases AST 3-fold and causes a 50% increase in ALT.
    2. The effect of exercise is minimal in women.

What is the distribution of SGPT (ALT) in the liver?

  1. This enzyme is present in cytosolic forms in the liver. The majority of the SGPT is present in the cytoplasm of liver cells.
  2. There is always a low level of this enzyme in the blood.
  3. This is a liver-specific enzyme of the transferases.
  4. The liver hepatocytes contain 3 to 4 times more AST (SGOT) than the ALT (SGPT).
  5. This is also normally found in bile, CSF, and saliva.
  6. It is not found in the urine unless there is a kidney lesion.
SGPT distribution in the liver cell

SGPT distribution in the liver cell

What is the mechanism of the liver cell injury?

  1. Any damage to the liver cells, SGPT enzyme, is released, specifically from liver cell necrosis.
  2. First, cytosolic SGPT is released, and in the case of necrosis, then mitochondria SGPT is released into circulation.
SGPT level depends upon the number of liver cells injured

SGPT level depends upon the number of liver cells injured

SGPT level depends upon the number of cells injured

SGPT level depends upon the number of cells injured

  1. SGPT activity persists longer than the SGOT.
  2. This enzyme is raised before clinical findings of jaundice are found.
  3. In viral hepatitis, the SGPT/SGOT ratio is greater than 1.
  4. Other than the viral cause, the SGPT/SGOT ratio is less than 1.

What are the variations and biochemical reactions of SGPT (ALT)?

  1. SGPT (ALT) catalyzes the reaction, and it is reversible.
  2. Pyridoxal-5‘- phosphate  (P-5-P) functions as coenzymes in the amino-transfer reaction.
    1. The P-5-P is bound to the apoenzyme and is a true prosthetic group.
    2. The P-5-P bound to the apoenzyme accepts the amino group from the first substrate, alanine, to form enzyme-bound pyridoxine-5- phosphate, and the first reaction product is pyruvate.
    3. This coenzyme increases the ALT activity by 20% in the normal serum.
    4. Hemolysis increases AST and ALT because of this enzyme activity in the RBCs compared to serum. This effect is more significant for AST than ALT.
SGPT (ALT) reaction principle

SGPT (ALT) reaction principle

What are the causes when SGPT is 1.5 to 8 times more than normal?

  1. Early, late, and subclinical hepatitis.
  2. Chronic hepatitis.
  3. Alcoholic hepatitis.
  4. Alcoholic fatty liver.
  5. Laennec’s cirrhosis.
  6. Chemical hepatitis.
  7. Passive congestion with centrilobular necrosis.
  8. Rye’s syndrome.
  9. Cholangitis.
  10. Hemochromatosis.
  11. Pancreatitis.
  12. Granulomatous infections.
  13. Neoplasia infiltration.

What are the causes when SGPT >8 to 10 times more than the normal value? 

  1. Mostly in acute viral hepatitis.
  2. Chronic active hepatitis.
  3. Infectious mononucleosis.

What are the causes when SGPT >30 times (20 or more) more than the normal value?

  1. Drug toxicity like acetaminophen in alcoholics and malnourished people.
  2. Viral hepatitis.

What is the SGPT level in various tissues as compared to serum?

  • Compared to serum (1 unit), the heart is 450 times; the liver is 2850 times; the kidney is 1200 times; skeletal muscle is 300 times; the pancreas is 130; the spleen is 80 times; the lung is 45, and RBCs 7 times.

What are SGPT (ALT) levels in various tissues as compared to the serum (one unit)?

Organs Times more as compared to the normal serum level
Liver 2850
Kidneys 1200
Heart 450
Skeletal muscle 300
Pancreas 130
Spleen 80
Lungs 45
RBCs 7
Serum 1

What is the AST (SGOT)/ALT (SGPT) ratio?

  1. ALT is the cytoplasmic enzyme in the liver, while AST is a cytoplasmic and mitochondrial enzyme with a wide distribution in various other tissues.

What is the Normal value of the SGOT/SGPT ratio?

  • 0.7 to 1.4

What is the AST/ALT ratio in liver diseases?

  1. AST/ALT ratio is typically <1, but infectious hepatitis becomes greater in the liver.

What are the causes when the AST/ALT ratio is usually greater than 1?

  1. The patient with alcoholic liver disease (cirrhosis). AST is more sensitive to alcoholic liver disease.
  2. Liver congestion.
  3. Metastatic tumor of the liver.

What causes an AST/ALT ratio of less than 1?

  1. Acute hepatitis is caused by drugs, viruses, and toxins.
  2. Viral hepatitis.
  3. Infectious mononucleosis.
  4. Extrahepatic cholestasis (normal or slightly decreased as 0.8).
  5. The ratio will be less accurate if the AST level is more than 10 times the normal.
Ratio of enzymes AST/ALT = <1 AST/ALT = >1
  • AST/ALT
  1. Acute hepatitis
  2. Viral hepatitis with extensive hepatocellular necrosis
  3. Infectious mononucleosis
  1. Alcoholic liver disease (Cirrhosis)
  2. Alcoholic patient with acetaminophen, causing extensive liver cell necrosis.
  3. Liver congestion
  4. Metastatic tumor infiltration of the liver
  5. Myocardial infarction
  6. Rhabdomyolysis
  7. Hemolytic anemia

What is the diagnostic application of the SGPT (ALT)?

  1. The best indicator for liver cell injury is when both SGPT and SGOT are raised.
    1. Higher levels are found in hepatocellular disorders than in extrahepatic or intrahepatic obstructive lesions.
    2. Levels of both enzymes may reach as high as 100 times. 20 to 50 times, the elevated level is frequently found.
  2. Measuring aminotransferases weekly is useful in hepatitis or other hepatic injuries.
  3. Because of the accurate measuring techniques, it can detect liver cell injury due to alcohol.
  4. It is used as a screening test for diagnosing hepatitis due to hepatotropic viruses, especially the hepatitis C virus in blood donors.
  5. In the liver’s metastatic carcinoma, ALT and AST are elevated 5 to 10 times. The AST (SGOT) level is higher than the ALT (SGPT) level. In the early stages of malignant liver infiltration, these enzymes are normal.
  6. ALT (SGPT) may be raised after intake of alcohol, delirium tremors, and after the administration of drugs like opiates, salicylates, and ampicillin.

What is the NORMAL SGPT (ALT) level?

Source 4

Age Male U/L Female U/L
Newborn 12 months 13 to 45 13 to 45
one to 60 years 10 to 40 7 to 35
60 to 90 years 13 to 40 10 to 28
>90 years 6 to 38 5 to 24

Source 2

  • Adult / child = 4 to 36 unit/L at 37 °C
  • Elderly = slightly higher than the adult
  • Infants = Maybe twice as high as adult

Another source

  • Men = 10 to 30 units /L (some labs normal is 10 to 40 U/L).
  • Women = 9 to 25 units /L (Some labs normal is 10 to 28 U/L).
  • Children are two times adults’ value.
    • In children, it is raised because of bone activity, which is normal for them.
    • The adult level is achieved by 6 months of age.
    • Males are slightly higher than females.

What are the causes of increased SGPT (ALT) levels?

  1. Viral hepatitis. There is a markedly increased level.
  2. Drug-induced hepatitis.
  3. Chronic hepatitis.
  4. Infectious mononucleosis.
  5. Intrahepatic cholestasis.
  6. Cholecystitis.
  7. Active cirrhosis.
  8. Metastatic tumors of the liver.
  9. Obstructive jaundice.
  10. Alcoholic cirrhosis.
  11. The mild increase is seen in :
    1. Myosotis.
    2. Pancreatitis.
    3. Myocardial infarction.
    4. Shock.
    5. Infectious mononucleosis.
  12. Alcohol-acetaminophen syndrome.
  13. A significant increase in levels has been in acute liver diseases.
    1. A moderately increased level is seen in chronic liver diseases and muscle trauma.
    2. Myositis, Myocardial infarction, and infectious mononucleosis show a mildly increased level.

What is the SGPT (ALT) pattern in Acute Viral hepatitis?

  1. This rises before the appearance of jaundice.
  2. The peak level occurs between 7 to 12 days of jaundice.
  3. Then there is a gradual decrease in the level.
  4. Normal level after 3 to 4 weeks of the onset of jaundice.
  5. AST/ALT ratio, which is normally <1, becomes greater > than 1.
SGPT level in acute viral hepatitis

SGPT level in acute viral hepatitis

What are the conditions showing increased SGPT levels?

Clinical condition
The rise in SGPT level with reference to the normal value
Viral hepatitis and liver diseases may reach 100 times
Infectious hepatitis ALT > AST
Toxic hepatitis Extremely high level
Infectious mononucleosis 20 times
Intrahepatic cholestasis maybe raised
Extrahepatic cholestasis Very high level
Cirrhosis 4 to 5 times or higher
Metastatic carcinoma 5 to 10 times
 Acute myocardial infarction within normal limits or a very mild increase
Progressive muscular dystrophy It may reach 8 times
Dermatomyositis It may reach 8 times

Critical value:

  •  >9000 U/L  seen in Alcohol-acetaminophen syndrome.
    This level can distinguish it from alcoholic or viral hepatitis.

What are the important facts about SGPT?

  1. AST (SGOT) is always raised in acute myocardial infarction, where ALT (SGPT) will be normal unless there is damage to the liver.
  2. ALT  (SGPT) is more raised in acute hepatobiliary obstruction than AST (SGOT).
  3. ALT (SGPT) is more specific than AST (SGOT) for liver cell injury.
  4. The AST/ALT ratio is higher in alcoholic liver diseases.
  5. AST (SGOT) is more sensitive to alcoholic liver cell injury.

What are the main features of  SGPT (ALT) and SGOT (AST)?

Clinical parameters SGPT (ALT) SGOT (AST)
Normal range 5 to 35 IU/L 10 to 40 IU/L
Half-life in blood 35 to 57 hours (3 to 5 days) 12 to 22 hours
  • Distribution in the body
  1. The Main is the liver
  2. Low concentration in other tissues
  1. It is more in the heart than the liver
  2. It is present in skeletal muscles, the brain, and the kidneys
Location in the liver cells It is present in the cytoplasm only It is present in cytoplasm and mitochondria
Change with acute inflammatory conditions It is extremely sensitive It is moderately sensitive
The rise in metastatic or primary neoplasm It is moderate or no change It is markedly increased
In cirrhosis It is a mild to moderate increase It moderately increases
In acute myocardial infarction It is a mild to moderate increase It markedly increases

Questions and answers:

Question 1: What is the half-life of SGPT?
Show answer
It is 3 to 5 days (35 to 57 hours)
Question 2: What is the best indicator of liver cell injury, SGOT or SGPT?
Show answer
SGPT is more specific for the liver cell injury.
Question 3: Is there any role of RBCs hemolysis in the level of SGPT.
Show answer
Yes, RBCs hemolysis will increase the SGPT level because of the presence in the RBCs.

Possible References Used
Go Back to Chemical pathology

Comments

Raja Mondal Reply
July 21, 2020

MY SGPT is 88 U/L and SGOT is 63. What kind of prevention should taken by me . I am just 24

Dr. Riaz Reply
July 21, 2020

You should have a complete Liver function test and viral hepatitis profile. Keep on checking SGPT and SGOT at least every three months.

jahangeer Khan Reply
August 13, 2020

My son’s test report is SGPT (ALT) 90 plaease tell me how to treat it and what medicine to use

Dr. Riaz Reply
August 13, 2020

Dear
This SGPT is raised. Please advise complete liver function test with viral profile HBV, HCV. Then best is to consult some good hepatologist or physician.

Tarun Reply
August 26, 2020

My SGOT IS 51
SGPT IS 72
What to do

Dr. Riaz Reply
August 26, 2020

You should have a complete liver function test and hepatitis profile (HBV, and HCV). If these are abnormal then consult the physician.

Lenard Concepcion Reply
September 6, 2020

Good day,
my sgpt is 56 U/L
my sgot is 59 U/L
I’m 34 y/o male. had muscle pain a few days ago due to my new squat exercise routine before taking this test. Is my muscle pain connected with my sgpt sgot levels? should i be worried? thank you

Dr. Riaz Reply
September 6, 2020

Dear SGOT/SGPT are raised. You should have total bilirubin, direct and indirect, alkaline phosphatase, and gamma GT level. If these are raised then please consult physician for further work-up.

Samidha Reply
September 14, 2020

My SGPT 79 & SGOT 48 & GGTP 75
Please suggest

Dr. Riaz Reply
September 15, 2020

Please advise liver function tests including viral profile and ultrasound abdomen. Consult some good physicians.

Samidha Reply
September 14, 2020

My SGPT 79 SGOT 48 GGTP 75
Please suggest

Dr. Riaz Reply
September 15, 2020

Please advise liver function tests and ultrasound of the abdomen. Consult some good physicians.

Ratan roy Reply
October 17, 2020

My bilirubin 15.5 and sgpt 250 what should I do?

Dr. Riaz Reply
October 17, 2020

Bilirubin is too high. Please advise the complete liver function test, ultrasound abdomen, and consult a good physician.

Dil jahan Reply
November 6, 2020

My alt sgpt is 10 U/l
Is it normal

Dr. Riaz Reply
November 7, 2020

Sure it is normal.

Shreya gupta Reply
October 21, 2020

Hi i am 24 year old female i have SGOT 52and SGPT 81.5 what should i do. Else every thing in my liver and blood profile is normal.

Dr. Riaz Reply
October 21, 2020

Please check your hepatitis viral profile. Please rule out any medication. Even aspirin can disturb the LFT.

Mitesh m Darji Reply
November 10, 2020

i m covid patient and my SGPT is 101. and CRP lavel is 0.6 so please suggest what to do

Mitesh m Darji Reply
November 10, 2020

hi
i m covid patient and my sgpt is 101

Dr. Riaz Reply
November 10, 2020

Please advise complete liver function tests to find any other abnormal values. You definitely need treatment for the Covid. Now, a day’s most doctors are prescribing steroids. Please consult some good physicians.

Bhavar Reply
December 11, 2021

My sgpt is 110 in liver function test rest is in normal range what it say

Fardosh Reply
November 12, 2020

Hi my mum 54 years old and her SGPT 52 is it normal.

Dr. Riaz Reply
November 13, 2020

It is the upper limit. Please advise the complete liver function test.

Rajat Bajaj Reply
November 13, 2020

My sgot is 33 and SGPT 72, is it serious ?
age 32 M
tested in fever 100 F

Dr. Riaz Reply
November 13, 2020

SGOT is normal, but SGPT is mildly raised which may be due to some medicine like Aspirin. Please repeat after 2 weeks.

Mary Reply
November 28, 2020

My lft result
Liver Function Test. Normal
Bilirubin -Total. : 0.5 mg/dl. 1. 0
Bilirubin – Direct. : 0.2 mg/dl upto 0.4
Bilirubin Indirect. : 0.3 mg/dl 0.2-0.6
SGOT/AST;Aspartate Aminotransferas
: 29 U/L Males : upto 35 U\L
Females : upto 31 U\L
SGPT/ALT;Alanine Aminotransferase
: 34 U/L Males : upto 45 U\L
Femaless : upto 34 U\L
Alkaline Phosphatas. : 78 IU/L
Adults : 18 – 115
Upto 12 yrs : 54 – 369
Total Protein. : 6.4 gm/dL
6 .4 – 8.3 g/dl
Albumin Serum. 3.7 gm/dL
3.5 – 5.5
Globulins. : 2.7 gm/dL 1.8 – 3.4
A/G Ratio. : 1.4:1 2:1
Technology used : Automated procedure On EM 200
I am 51 years
Some values are in boundary
What it indicate
Need more test?

Dr. Riaz Reply
November 28, 2020

Mostly your tests are in the normal range. I don’t think so. If you have any symptoms then consult a physician and do the tests which he/she thinks are needed.

Liton Saha Reply
December 21, 2020

MY SGPT is 28 U/L and (HBV) DNA is Undetected. What kind of prevention should taken by me . I am just 35

Dr. Riaz Reply
December 21, 2020

Vaccination for HBV infection is available. I will suggest you get vaccinated.

Akhlaq Ahmed Reply
December 23, 2020

Hi Dr. Riaz, I am diabetic patient and a stone in my gallbladder with no pain, four months ago SGPT result was 44 U/L , recent test result SGPT is 66 U/L. my age is 41.

Dr. Riaz Reply
December 23, 2020

I will suggest to control diabetes and get operated on for gall stones. I will suggest consulting the surgeon because gall stones may give rise to a mild increase in liver enzymes.

Prabhat kumar singh Reply
January 6, 2021

TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 74.6 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.79 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.25 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.55 mg/dl 0-0.9
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 128.73 U/l < 35
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 90.6 U/l < 45
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 17.5 U/l < 55
PROTEIN – TOTAL PHOTOMETRY 9.05 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 5.2 gm/dl 3.2-4.8
SERUM GLOBULIN PHOTOMETRY 3.85 gm/dL 2.5-3.4
SERUM ALB/GLOBULIN RATIO CALCULATED 1.35 Ratio 0.9 – 2
Please correlate with clinical conditions
Please sugges me what I have to do…..
Is this a indication of liver cerosis

Dr. Riaz Reply
January 6, 2021

Most tests are normal except for SGOT and SGPT. Please rule out alcohol intake and pain killers.

Shashvat dubey Reply
January 8, 2021

Hi Sir,
My SGOT – 62.88
SGPT – 132.41
Serum bilirubin – 0.41
Direct – 0.19
Indirect – 0.22
Serum protein – 6.94
Serum Alkaline phosphatase :- 68.86
Albumin – 4.78
Globulin – 2.16
A/G ratio – 2.21

My age 32 .

Is their any thing serious ?

Dr. Riaz Reply
January 8, 2021

Your SGOT/SGPT is raised, showing liver cell necrosis. Please rule out alcohol and pain killer therapy.

paresh Reply
January 11, 2021

my SGPT is 84 is it to much high ?

Dr. Riaz Reply
January 11, 2021

I can say this is raised. You should do a complete liver function test. I will suggest repeating your test after 2 to 3 months.

Sayanika Reply
January 29, 2021

My sister’s SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?

Isha Reply
January 29, 2021

My sisters SGOT is 31.5 and SGPT is 39.6. Other parameters in liver function test is normal. She is 23 yrs old. Is it serious?

Dr. Riaz Reply
January 29, 2021

These levels are in the normal range; I don’t think is serious. If you are very conscious, repeat liver function tests (LFT) after 2 to 3 months.

Talha Reply
September 26, 2023

Sir my sgpt k 171 or 119 and lfts and ultrasound are normal

Dr. Riaz Reply
September 28, 2023

Your SGPT is raised, please check viral profile (HBV, HCV).

BHIZHI Reply
February 5, 2021

hi! my SGPT US 61.45
IM 31 YEARS OLD.

Dr. Riaz Reply
February 5, 2021

SGPT is slightly raised. You should have done a complete liver function test (LFT).

Sukanya Y Reply
February 10, 2021

Sir,
BILIRUBIN-TOTAL 0.30 mg/dL 0.20 – 1.20 Diazonium salt
BILIRUBIN-DIRECT 0.10 mg/dL 0.0-0.3 Spectrophotometric
BILIRUBIN-INDIRECT 0.20 mg/dL 0.0-1.10 Direct measure
ALKALINE PHOSPHATASE 99.00 U/L 38-126 PNP
AST/SGOT 29.0 U/L 17-59 UV with P-5-P
ALT/SGPT 15.0 U/L <35.0 UV with P-5-P
AST:ALT RATIO 1.93 Ratio Upto 1.3 Calculated
PROTEIN, TOTAL 6.80 g/dL 6.3-8.2 Biuret
ALBUMIN 4.10 g/dL 3.5 – 5.0 Bromocresol Green
GLOBULIN 2.70 g/dL 2.0-3.5 Calculated
A/G RATIO 1.52 0.8-1.2 Calculated

AST/ALT ratio and A/G ratio are not normal as per the above. Kindly analyse and advise.

Dr. Riaz Reply
February 10, 2021

Your LFT values are normal. I may not give importance to calculated values unless the values were abnormal.

ANAND UNNIKRISHNAN Reply
February 17, 2021

FBS 93
HDL 52
LDL 129
VLDL 21
BILIRUBIN 105
SGOT 80
SGPT 92
Kindly analyse and advise

Dr. Riaz Reply
February 17, 2021

FBS, HDL, VLDL are in the normal range. LDL can be decreased more. Your Liver function tests are abnormal. You must consult a hepatologist.

Love Reply
May 17, 2021

Sgpt- 47
Sgot- 85
Ratio- 1.5
Bilirubin- 0.4

Dr. Riaz Reply
May 18, 2021

Your SGPT and SGOT are mildly raised. Please get detailed liver function tests and viral hepatitis profile (HBV, HCV). I hope you are not taking painkillers or alcohol or any other drugs?

KAMRAN FAROOQ BHAT Reply
February 26, 2021

My sgot is 51
Sgpt 61
Billirubin 1.8
Blood sugar level 87
TSH 7.5
Ultra sound shows mild fatty liver.
What is your advice?
I feel fatigue

Dr. Riaz Reply
February 26, 2021

Your SGOT and SGPT are slightly above the normal value. But your TSH (If it is mU/L) level is too high, indicating hypothyroidism. Hypothyroidism can lead to feelings of fatigue. Please read the following link and have a complete workup of thyroid functions.
https://www.labpedia.net/thyroid-part-2-thyroid-stimulating-hormone-tsh-thyrotropin/

JP Reply
March 1, 2021

SGPT – 102
SGOT – 6
Please advise

JP Reply
March 1, 2021

SGPT – 102
SGOT – 6

Please advise

Dr. Riaz Reply
March 1, 2021

SGPT represents a problem in the liver, and SGOT should also need to be raised. This is an unusual picture. I will advise repeating complete liver function tests and viral hepatitis markers as well.

Mir Marri Reply
March 4, 2021

Dr sb i have got my test reports. My sgpt is 139 & Hbv pcr is 892. How is the result dr sb. Waiting for ur kind answer.

Dr. Riaz Reply
March 4, 2021

SGPT 139 is increased. HBV PCR value needs their normal range. It would be best if you had a physician consultation for the treatment.

Hema Malini Reply
March 7, 2021

TEST NAME TECHNOLOGY VALUE UNITS NORMAL RANGE
ALKALINE PHOSPHATASE PHOTOMETRY 61.8 U/L 45 – 129
BILIRUBIN – TOTAL PHOTOMETRY 0.78 mg/dl 0.3-1.2
BILIRUBIN -DIRECT PHOTOMETRY 0.24 mg/dl < 0.3
BILIRUBIN (INDIRECT) CALCULATED 0.54 mg/dl 0-0.9
GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY 19.1 U/l < 38
ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY 34.4 U/l < 31
ALANINE TRANSAMINASE (SGPT) PHOTOMETRY 44.4 U/l < 34
PROTEIN – TOTAL PHOTOMETRY 7.1 gm/dl 5.7-8.2
ALBUMIN – SERUM PHOTOMETRY 4.2 gm/dl 3.2-4.8
SERUM ALB/GLOBULIN RATIO CALCULATED 1.45 Ratio 0.9 – 2
SERUM GLOBULIN PHOTOMETRY 2.9 gm/dL 2.5-3.4
Please correlate with clinical conditions.
Method :
ALKP – MODIFIED IFCC METHOD
BILT – VANADATE OXIDATION
BILD – VANADATE OXIDATION
BILI – DERIVED FROM SERUM TOTAL AND DIRECT BILIRUBIN VALUES
GGT – MODIFIED IFCC METHOD
SGOT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
SGPT – IFCC* WITHOUT PYRIDOXAL PHOSPHATE ACTIVATION
PROT – BIURET METHOD
SALB – ALBUMIN BCG¹METHOD (COLORIMETRIC ASSAY ENDPOINT)
A/GR – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
SEGB – DERIVED FROM SERUM ALBUMIN AND PROTEIN VALUES
Hi Dr. Riaz, Am i suffering from anything serious? Please advice. Thanks

Dr. Riaz Reply
March 7, 2021

Only your SGOT and SGPT are mildly raised. Rest all tests are normal. I will advise eat more fruits and repeat only these two tests after 2 to 3 months.

Hema Malini Reply
March 7, 2021

Does low uric acid in plasma or serum, an indication of any kidney disorder?

Dr. Riaz Reply
March 8, 2021

You have not told how low is the blood uric acid level. Please read the following link, and this may be helpful for you.
https://www.labpedia.net/uric-acid-level-blood-uric-acid/

Narendra Shekhar Reply
March 22, 2021

Sgpt -132
Sgot – 98
Alkaline phosphate -242
Bilirubin – 2.1

Dr. Riaz Reply
March 22, 2021

Your LFT is abnormal and needs a consultation by the physicians.

maria rahman Reply
March 24, 2021

my sgpt (alt)is 60u/l and sgot (als) is 28 is it normal?

Maria Rhman Reply
March 24, 2021

my age is 18 my sgpt(alt)is 60u/l and sgot(ast)is 28 is it risky?

Dr. Riaz Reply
March 24, 2021

SGPT is slightly raised, but SGOT is normal. Please repeat both tests after one month. Take more fruits during this period. Avoid aspirin.

bon Reply
March 31, 2021

Sgot is 33.9 and SGPT is 46.2

Dr. Riaz Reply
March 31, 2021

SGOT looks normal and SGPT slightly above normal. My suggestion is to repeat the LFT (SGPT) after one month.

Sagar patil Reply
March 31, 2021

Hello sir
My wifes sgpt 34 and sgot is 42.she is 7 months preganant.. Also she is taki g aspirin as per doctors advice..is thia range is normal?

Also the d dimer is 841..

Dr. Riaz Reply
April 1, 2021

These values are normal. Because the aspirin may increase SGOT, when she stops aspirin, I hope SGOT will also be below 40. Give her more fruits that may help her.

Sagar Reply
April 1, 2021

What about d dimer sir..

Dr. Riaz Reply
April 1, 2021

Please see the following link for D-dimer.
https://www.labpedia.net/d-dimer-test-fragment-d-dimer/

Saranraj
November 1, 2022

Hi Doctor
I’m 34 Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet for 15 days(3 times in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
My Report taken on 23.10.22 :
LIVER FUNCTION TEST with GGT
SERUM G G T 210.5 U/L
SERUM SGOT 900 U/L
SERUM SGPT 1549 U/L
SERUM BILIRUBIN TOTAL :6.71 mg/dl
SERUM BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
SERUM ( Hepatitis B ) Non reactive 0.36
SERUM ANTI HCV (C VIRUS) Nonreactive (0.09)

Pls suggest Doctor ,Can I continue the Liv 52 tablet another one week?

Dr. Riaz
November 1, 2022

Your Liver function tests are abnormal. It is good that HBV and HCV are negative. To see the effect of the drug you are taking, please repeat LFT after two weeks. If LFT is improved, you can continue the medications as your physician advises.

Sagar patil Reply
April 1, 2021

What about d dimer sir?

Jay Reply
April 12, 2021

my SGPT is 87.77 and my SGOT is 92.47 what should i do? thank u

Dr. Riaz Reply
April 12, 2021

Your LFT is abnormal; you need further workup like complete LFT with gamma-GT. Ultrasound of abdomen. If you are using alcohol, first quit and recheck LFT after one month.
If no improvement, then consult a hepatologist or gastroenterologist.

RAHUL YADAV Reply
April 15, 2021

Sir my LFT test is
SPGT LEVEL 199
SOGT LEVEL 65
BILUBRIN LEVEL 0.80
IS IT IN DANGEROUS LEVEL

Dr. Riaz Reply
April 15, 2021

Your liver function tests (LFT) are abnormal. No doubt, bilirubin is normal. This needs to rule out liver cell necrosis like alcohol intake, viral hepatitis, and some drug use.
It would be best if you had thorough work up to find the cause of abnormal LFT.

Robin kumar Reply
April 16, 2021

HDL / LDL Cholesterol Ratio
Value: 0.50 ratio
Normal Range:-ratio – -ratio

SGOT/AST
Value: 54.00 U/L
Normal Range:0U/L – 50U/L

SGPT/ALT
Value: 92.20 U/L
Normal Range:0U/L – 50U/L

GGTP (Gamma GT)
Value: 71.00 U/L
Normal Range:0U/L – 55U/L

SGOT/SGPT Ratio
Value: 0.59 ratio
Normal Range:0.7ratio – 1.4ratio

Proteins, Serum
Value: 7.26 g/dL
Normal Range:6.6g/dL – 8.3g/dL

Albumin, Serum
Value: 4.65 g/dL
Normal Range:3.5g/dL – 5.2g/dL

A/G Ratio
Value: 1.78 ratio
Normal Range:1.2ratio – 2.2ratio

Bilirubin Total, Serum
Value: 1.07 mg/dL
Normal Range:0.3mg/dL – 1.2mg/dL

Bilirubin Direct, Serum
Value: 0.20 mg/dL
Normal Range:0.0mg/dL – 0.2mg/dL

Bilirubin- Indirect, serum
Value: 0.87 mg/dL
Normal Range:0.1mg/dL – 1.0mg/dL

Alkaline Phosphatase, Serum
Value: 109.00 U/L
Normal Range:30U/L – 120U/L

please suggest. Is it critical?

Dr. Riaz Reply
April 16, 2021

Your SGOT, SGPT. and Gamma GT is raised. It would help if you had further workup to rule out any disease of the liver. Please consult the physician for further workup.

George Reply
April 30, 2021

Hi I’m George ALT/SGPT 14.08 U/L 14.08 ukat/L, please help me understand my findings. Thank you and Godbless

Dr. Riaz Reply
April 30, 2021

SGPT 14.08 U/L is in the normal range, and no need to worry.

George Reply
May 1, 2021

Thank you so much Dr. Riaz
You ease my worries. Thank you for helping me.
More power and Godbless

nasir Reply
May 8, 2021

im 35 year old my last week report about sgpt leve is 77
and bilirubin leve is 0.37
every week i did my test and some time result shown sgpt level 80 then 60 then 65 then 35 then 55 then 89 then 77 and bilirubin leve is always normal. whats i do is this thing is dangerous or not

Dr. Riaz Reply
May 8, 2021

SGPT level fluctuations mean that some minor injury in the liver, the causes may be viral hepatitis C, alcohol intake, some pain killer medications. You have to rule out these possibilities.

nasir Reply
May 9, 2021

Thanks for the replay dear , few month ago i was sick and i used antibiotics medicines for 20days, after that is issue is rise ( increase of sgpt) i don’t use alcohol..
i used using the Estar tablet 10mg twice in a week, is this tablet is harmful in high SGPT or not please answer on this,,, and today on 5//9/2021 i repeat my sgpt test that was 61 befor is that was 77 in last week,,, i try to control this on proper diets,, actually im food lover and i like to eat fish and meals but now a days im on diet,, is this problem can be handle on diet or i need to visit doctor
thanks again for your replay to my message Doctor

Dr. Riaz Reply
May 9, 2021

Your LFT is definitely abnormal. I will suggest consulting some hepatologist or gastroenterologist.

nasir Reply
May 10, 2021

Thanks
yes i have ulcer problem from last 7 year …i just want to know that ,can i use Estar tablet 10mg , because if i dont use this tablet then i feel bad

Dr. Riaz Reply
May 10, 2021

I think you can use Estar. For more details, see this link.
https://www.webmd.com/drugs/2/drug-10716/estar-topical/details#:~:text=This%20medication%20is%20used%20on,the%20growth%20of%20skin%20cells.

nasir Reply
May 10, 2021

I will see the link sir .. and thanks for your help I will remember you in my prayers

Natassa Reply
May 19, 2021

SGPT/ALT is 9 and SGOT/AST is 11. The SGPT/ALT is very low. What does it mean? I am 50.

Dr. Riaz Reply
May 19, 2021

I will say that these tests are normal and no need to worry.

chaminda Reply
May 19, 2021

my SGOT 36.0 U/L AND SGPT 42.6 U/L Please advice

Dr. Riaz Reply
May 19, 2021

SGOT is normal, and SGPT is boerder-line. Please take more fruits and repeat the liver function test after one month and then let me know the result.

Avinash Reply
May 22, 2021

Sgot 43
Sgpt 50
Should I worry?
Age 25

Dr. Riaz Reply
May 22, 2021

Your SGOT/SGPT are mildly raised. You need to worry and find the cause like viral hepatitis, and some drugs may increase. Better consult a physician to find the cause.

M Singh Reply
May 30, 2021

Sgot 47
Sgpt 88
S Bilurubin total 1.0
ALP 170
RFT all normal values
Blood sugar 70

Should I worry?
Age 36
Was taking 2-3 drinks daily from last 20-25 days

Dr. Riaz Reply
May 31, 2021

I think your SGOT/SGPT is raised due to alcohol intake. I will suggest stopping alcohol for at least 2 to 3 months till these enzymes are normal. Then you can take off and on alcohol but not regularly. Otherwise, you will develop cirrhosis of the liver, which ultimately leads to liver failure.

rivaldo Reply
June 12, 2021

Dear Dr. Diaz
I wonder why AST is specifically more elevated in case of periportal necrosis in Preeclampsia ?

Best, regards

Rivaldo

Dr. Riaz Reply
June 12, 2021

You may see hypertension, proteinuria, oliguria, pulmonary edema, thrombocytopenia, and elevated transaminase level in preeclampsia. I think these are the complications of preeclampsia.

Maria Reply
July 5, 2021

my sister’s sgpt test’ report says that she has 186 U/L. is it too much? what we can do for her? she is only 9 years old.

Dr. Riaz Reply
July 14, 2021

What is SGOT, total bilirubin and alkaline phosphatse? Please also ask for viral markers (HBV. HCV).

Yuvaraj Reply
July 28, 2021

BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl

LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)

Dr. Riaz Reply
July 29, 2021

I don’t know your age. All your parameters are normal except SGOT/SGPT, Which indicates liver cell injury. I hope you are not taking alcohol. Would you please check your viral hepatitis profile (HBV, HCV)?

Yuvaraj Reply
July 29, 2021

36 age sir

Yuvaraj Reply
July 29, 2021

My age 36, I consume alcohol daily, What should I do Sir ?

Uvaraj Reply
July 29, 2021

BLOOD – SUGAR(F)- 85 msg/dl
BLOOD – SUGAR(PP) at 1 1/1hrs – 95 msg/dl

LIVER PROFILE:
BILIRUBIN(TOTAL) – 1.1 mg/dl
BILIRUBIN(DIRECT)- 0.4 mg/dl
BILIRUBIN(INDIRECT)- 0.7 mg/dl
SGOT- 93 IU/L
SGPT – 91 IU/L
SERUM ALK PHOSPHATASE
IFCC – 88 U/L
PROTEIN
(Serum/BCP ) : 7.5 g/dl
ALBUMIN : 4.9 g/dl
GLOBULINS : 2.6
A/G RATIO : 1.8
(Serum/ Arsenazo III)

Pratiksha Kumari Reply
July 31, 2021

I’m 26 female and my SGPT is 43.4 rest everything is normal

Also creatinine serum is 0.86
Do I need to worry and wha further tests should be done?

Dr. Riaz Reply
July 31, 2021

I don’t think you need to worry. Just repeat SGPT after 2 to 3 months.

Rahul Reply
August 7, 2021

Sgpt-1200 u/ml
Sgot-400 u/ml
Billirubin is 4.2
My age is 49 .. What to do?

Dr. Riaz Reply
August 7, 2021

Your liver function tests are abnormal, and you must have clinical jaundice. You should check your viral profile like HBV, HCV, and HAV.

Rahul Reply
August 7, 2021

Doctor, sgpt and sgot is in u/lit

Sia Reply
August 11, 2021

my sgpt is 31u/l and i’m a 20 yr old female . is it high?

Dr. Riaz Reply
August 11, 2021

What about SGOT?. But this is in the normal range.

Sia Reply
August 11, 2021

MY DR. JUST ASKED ME TO GET THAT SGPT TEST DONE ALONG WITH THYRIOD. WHEN MY SGPT RESULTS WERE OUT THEY SAID IN FEMALES IT HAS TO BE 21U/L AND BELOW AND ACCORDINGLY MY LEVELS ARE HIGH. PRETTY CONFUSED AS MY REPORT INDICATES NORMAL WHERE AS DR. SAYS ITS NOT, AND THEN THEY ASKED ME TO DO FIBRO SCAN SAYING I MIGHT HAVE A FATTY LIVER AND AFTER DOING THAT MY RESULT WAS NORMAL.

Deepti Reply
August 21, 2021

My SGOT is 47 and SGPT is 16. I am 22 years old female. I have lost my appetite and doesn’t feel hungry at all.

Dr. Riaz Reply
August 21, 2021

SGOT is the upper limit of normal. I will advise you to repeat the complete liver function test and ESR after at least 1 to 2 months. Meanwhile, avoid aspirin intake. Are you taking any other medications?

Masroor Reply
May 20, 2022

Sir my LFT(6 para) test is
Serum bilirubin is 6.5 total
Serum bilirubin is 4.5 direct
Serum bilirubin is 2.0 indirect
Sgpt(AlT) is 1957
Alkaline phosphate is 259
Gamma GT is 44

Sir it can be normal my niece age is 18 years

Dr. Riaz Reply
May 20, 2022

These liver function tests are abnormal, indicating hepatitis. Have you done viral profiles like HBV and HCV? She needs consultation to find the cause of jaundice.

GDS Reply
September 13, 2021

Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause and what to prevent. Please guide.

JS Reply
September 13, 2021

Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause and what to prevent. Please guide.

JS Reply
September 13, 2021

Hello Sir,
I am JS, 42, Female. My SGOT is 35, SGPT is 73, GGTP is 57. Cholesterol Total Serum is 176, Glucose Fasting is 111. I do not take alcohol. What is the cause and what to prevent. Please guide.

Dr. Riaz Reply
September 13, 2021

Your SGPT is raised, which indicates liver cell injury.
Fasting glucose level is in the normal range. Cholesterol is also not high.
You need a thorough workup for the liver. I hope you are not taking any painkillers?

GDS Reply
September 13, 2021

Hello Sir,
I am GDS, 45, Male. My SGOT is 40, SGPT is 55, GGTP is 80. Cholesterol Total Serum is 239, Glucose Fasting is 154. I do not take alcohol. What is the cause and what to prevent. Please guide me.
Regards

Dr. Riaz Reply
September 13, 2021

Your fasting glucose favor diabetes mellitus, so you should rule out diabetes mellitus. Please check fasting glucose level at least three times, and if still, it is more than 126 mg/dL, then it is diabetes mellitus.
Your cholesterol level is raised.
It would be best if you had a physical checkup to rule out Diabetes mellitus.
Also, it would be best if you had diet control for cholesterol.

NILESH BHASKAR NAIK Reply
September 16, 2021

Hi DOCTOR, I RECENTLY DID MY LFT AND RESULTS ARE SGOT 56.4, SGPT 54.7, DIRECT AND INDIRECT BILLIRUBIN SKIGHTLY INCREASED,
I HAVE GILBERT’S SYNDROME ALSO I DID MY SONOGRAPHY, EVERYTHING WAS NORMAL. EXCEPT SLUDGE IN GALL BLADDER, WHAT SHOULD I DO?

Dr. Riaz Reply
September 16, 2021

This is a benign condition and there is no specific treatment. Gilbert’s syndrome is a life-long disorder.
You have to avoid some of the drugs. here are a few of those.
1. Gemfibrozil, for lowering cholesterol.
2. Statins, also used for reducing cholesterol, when taken with gemfibrozil.
Please see this links:
https://labpedia.net/gilberts-syndrome-diagnosis/

Jugitasharma Reply
September 18, 2021

Sir I am 28 years old female my SGPT IS 49
Alkaline phosphate is 102, GGTP is 15 are my reports normal sir??

Dr. Riaz Reply
September 18, 2021

These values are normal except for SGPT, which is the normal upper range. You can repeat SGPT, SGOT after 2 to 3 months.

Sobia Reply
September 22, 2021

My sgpt is 165 I am 34 years old

Dr. Riaz Reply
September 22, 2021

Your SGPT is raised, indicating liver cell injury. Would you mind letting me know complete liver function tests and Ultrasound abdomen report?

Sussie Reply
September 26, 2021

Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.

VSG: 22 mm/hr
Liver Profile:
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L

Sussie Reply
September 26, 2021

Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.

Liver Profile:
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L

Sussie Reply
September 26, 2021

Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.
Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L

Dr. Riaz Reply
September 26, 2021

Your tests are normal, except GGT and SGPT are normal upper range. This may be due to pain killer intake or any other medicines. I will suggest you, please repeat after 2 to 3 months only GGT, SGOT, and SGPT.

Sussie Reply
September 26, 2021

Hi, Dr. Please, read my results:
I am a girl and I am 22 years old.

Bilirubin (Total): 1.10 mg/dL
Bilirubin (Direct): 0.30 mg/dL
Bilirubin (Indirect): 0.80 mg/dL
Total Proteins: 7.0 gr/dl
Serum Albumin: 4.2 gr/dl
Globulin: 2.8 gr/dl
Alkaline Phosphatase: 120 U/L
GTO: 40 Ul/ml
GPT: 45 Ul/ml
GGT: 59 U/L

Rashmi Reply
October 5, 2021

My CBC report:
Platelete count is 89000
Lymphocytes 51%
MCH 25.88%

LFT test Reports
Only SGPT is raised upto 38 IU/L all other Reports are normal… Plz suggest what to do next

Dr. Riaz Reply
October 5, 2021

Platelets are low; lymphocytes are more than the normal range. SGPT and MCH is normal. This patient needs workup. Why are platelets low?

Ankit Kumar Reply
October 21, 2021

My LFT report:- Impression (Grade 1 fatty liver)
SGOT:- 35 IU/L
SGPT:- 71IU/L
Bilirubin Total:- 2.6 mg/dl
Bilirubin Direct:- 1.3 mg/dl
Bilirubin indirect:- 1.3mg/dl

In every test, I have noticed my bilirubin level has been elevated what is the reason behind it. I have consulted a few doctors but they have not been able to find the reason behind it.

Dr. Riaz Reply
October 22, 2021

Your case fits into Dubin-johnson syndrome, but your SGPT level does not favor it.
https://labpedia.net/dubin-johnson-syndrome-diagnosis/
See above link.
I hope you are not a drinker. Bilirubin above 2 mg/dL will show yellowness of the eyes. Would you please check your hemoglobin, viral hepatitis profile, and urine examination?
Then let me know the results.

Manish Reply
October 29, 2021

My complete report as follows
LIVER & KIDNEY PANEL, SERUM
(Reflectance Photometry,Direct ISE)
Bilirubin Total 0.60 mg/dL 0.30 – 1.20
Bilirubin Direct 0.11 mg/dL <0.30
Bilirubin Indirect 0.49 mg/dL <1.10
AST (SGOT) 37 U/L <50
ALT (SGPT) 80 U/L <50
GGTP 71 U/L <55
Alkaline Phosphatase (ALP) 108 U/L 30 – 120
Total Protein 6.73 g/dL 6.40 – 8.30
Albumin 4.20 g/dL 3.50 – 5.20
A : G Ratio 1.66 0.90 – 2.00
Urea 21.73 mg/dL 17.00 – 43.00
Creatinine 0.82 mg/dL 0.67 – 1.17
Uric Acid 7.43 mg/dL 3.50 – 7.20
Calcium, Total 8.89 mg/dL 8.80 – 10.60
Phosphorus 3.48 mg/dL 2.40 – 4.40
Sodium 138.70 mEq/L 136.00 – 146.00
Potassium 4.11 mEq/L 3.50 – 5.10
Chloride 104.14 mEq/L 101.00 – 109.00
These test has done on morning and last night I had alcohol… does it may refect in test
Kindly tell me what to do

Dr. Riaz Reply
October 29, 2021

Definitely, alcohol will affect SGOt/SGPT and GGT levels. Your cholesterol level is also normal upper limit (borderline case). You have not mentioned the HDL.
LDL and VLDL are atherogenic and predispose to heart diseases. I will suggest quitting alcohol, and it will damage the liver.

Manish Reply
October 30, 2021

Test Name Results Units Bio. Ref. Interval
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130

Manish Reply
October 29, 2021

In addition
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130

Manish Reply
October 30, 2021

Test Name Results Units Bio. Ref. Interval
LIPID SCREEN, SERUM
(Spectrophotometry)
Cholesterol, Total 216.83 mg/dL <200.00
Triglycerides 137.73 mg/dL 40.00
LDL Cholesterol, Calculated 147.17 mg/dL <100.00
VLDL Cholesterol,Calculated 27.55 mg/dL <30.00
Non-HDL Cholesterol 175 mg/dL <130

Nawaz Shah Reply
November 1, 2021

My sisters SGPT level is 2080 and 0-35 is recommended in report. How bad it is??
Bilirubin 2.6
RBC count 5.35
Any suggestions

Dr. Riaz Reply
November 3, 2021

SGPT level and bilirubin are raised. There is liver cell injury. Would you please advise liver functions test and viral hepatitis profiles?

Himanshu Reply
November 7, 2021

Sgpt 46
Direct bilirubin 0.6
Others normal
Should I worry or continue eating everything?
I’m not alcoholic.
I have gastritis for 2 weeks also

Dr. Riaz Reply
November 7, 2021

Bilirubin level is normal. For gastritis, you need treatment. At least avoid spices.

Himanshu Reply
November 8, 2021

Can gastritis be cured without medicines by dietary changes sir?

John Reply
November 12, 2021

Hi doc my sgpt is 287 but other than that all my test are normal

My doc ask me to undergo liver ultrasound and these is what it says:

The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated

John Reply
November 13, 2021

Hi doc, my sgpt level is 287, so my doctor said to undergo liver ultra sound and this is my ultra sound says
The liver is normal in size with a span of 13.7cm. Its border is smootu but there is marke increase in the parenchymal echogenicity and the intrahepatic veins not visible. There is no focal lesion nor calcification
The common bile duct and intrahepatic ducts are not dilated
And another thing doc, i read in the internet that they need 5ml of blood for sgpt test
The clinic i went only got 1ml of my blood

Dr. Riaz Reply
November 14, 2021

SGPT is raised, you need a complete liver function test including gamma GT. 5 mL blood is ideal, but someone may get enough serum from one mL. Your SGPT indicates liver cell injury.

John Reply
November 16, 2021

Thank u doc, another thing doc
All my test are normal, only my sgpt is high
Thanks again doc.

Taxia Reply
November 16, 2021

Is SGPT 56, SGOT 29 normal? Took flagyl and librax for some days.
THank you in advance (man)

Dr. Riaz Reply
November 18, 2021

SGPT is raised (abnormal), but SGOT is in the normal range. SGPT indicates liver cell injury. When SGPT is raised, there should be a mild increase in the SGOT, which is not in your case. Better check both parameters after one month.

Mehedi hasan Reply
November 25, 2021

My name is Mehedi hasan. My test result from LABAID
HBsAg=Positive sample OD >10000 Cut-Off OD 1.0
Bilirubin=1.1 mg/dl
ALT(SGPT)=51 U/L
AST(SGOT)= 32 U/L
HBeAg= Negative
Anti-HCV= Negative
Anti-HBe= Positive sample OD 400 Cut-Off OD 100

Dr. Riaz Reply
November 25, 2021

These findings of HBsAg and HBeAg indicate chronicity. Your SGPT is mildly raised, but SGOT is normal. I will suggest keeping an eye on liver function tests or getting the treatment for the hepatitis B virus.

Emarshana Reply
November 27, 2021

Usually both ast and alt are high in hepatic metastasis?

Dr. Riaz Reply
November 27, 2021

In metastatic, infiltrate of carcinoma depends upon the involvement of the liver area. There may be raised AST/ALT and alkaline phosphatase levels.

Anil Kumar Reply
November 29, 2021

Sgot – 43 and Sgpt – 48 my age is 36 I need to consult doctor.

Anil Kumar Telluri Reply
November 29, 2021

Sgot – 43 and Sgpt – 48 my age is 36. Could I need to consult doctor.

Dr. Riaz Reply
November 29, 2021

You need to repeat complete liver function tests after 2 to 3 months, and then let me know the results.

O pk Reply
December 2, 2021

Bilirubin(total) – 0.59 mg/dl
Bilirubin(direct) – 0.15 mg/dl
Bilirubin (indirect) – 0.44 mg/dl
Sgot -52 iu/l
Sgpt – 135 iu/l
Alkaline phosphatase – 168 u/l
Total protein – 7.6 gm/dl
Albumin – 5.5 gm/dl
Globulin – 3.1 gm/dl
A/G ratio – 1.5
Ggt – 34 iu/l

Age – 22 , No smoke and drinking.
Pain in upper abdomen liver side
Emergency?

Dr. Riaz Reply
December 2, 2021

Your SGOT and SGPT are raised, indicating liver cell injury. Would you please rule out any use of drugs? Also, check your viral profile (HBV, HCV).

O pk Reply
December 2, 2021

No drug

Vishal Thakur Reply
December 5, 2021

Liver Function Test (LFT)
Serum Bilirubin, (Total)
Method: Diazo
1.06 mg/dl 0.2-1.2
Serum Bilirubin, (Direct)
Method: Diazo
0.34 mg/dl 0.0 – 0.5
Serum Bilirubin, (Indirect)
Method: Calculated
0.72 mg/dl 0.0 – 0.8
Aspartate Aminotransferase (AST/SGOT)
Method: IFCC
40.85 U/L 5 – 34
Alanine Aminotransferase (ALT/SGPT)
Method: IFCC
68.00 U/L 0 – 55
Alkaline Phosphatase (ALP)
Method: IFCC AMP Buffer
96.00 U/L 43 – 115
Gamma Glutamyl Transferase (GGT)
Method: IFCC
38.5 U/L 12-64
Serum Total Protein
Method: Biuret
8.22 g/dl 6.6 – 8.3
Serum Albumin
Method: Bromo Cresol Green(BCG)
5.01 g/dl 3.5 – 5.2
Serum Globulin
Method: Calculated
3.21 gm/dl 3.0 – 4.2
Albumin/Globulin Ratio
Method: Calculated
1.56 Ratio 1.2 – 2.5
SGOT/SGPT Ratio
Method: Calculated
0.60 Ratio 0.7 – 1.4

My age is 23. Is there anything need to worry.

Dr. Riaz Reply
December 5, 2021

Your SGOT and SGPT are mildly raised. Please repeat SGPT/SGOT after 2 to 3 months. Also, check your HBV and HCV status. I hope you are not taking any medicines?.

Vishal Thakur Reply
December 5, 2021

15 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and skipping breakfast. can this may be the reason?

Vishal Thakur Reply
December 5, 2021

15 days ago i met with a road accident then i took a pain killer otherwise no medicines. For past 2 weeks i am doing only lunch and dinner and skipping breakfast. can this may be the reason?

challa pavan Reply
December 7, 2021

hi…sir 5 day before sgpt test 45iu/l sgot 31iu/l but now today sgpt 576.8 sgot 509u/L I hv jaundice what happen sir….plz suggest

Dr. Riaz Reply
December 7, 2021

It means your liver function tests are abnormal. Would you please advise viral markers (HBV, HCV, and HAV)?

Bhavar Reply
December 11, 2021

My sgpt is 110 in liver function test rest is in normal range what it say

Dr. Riaz Reply
December 11, 2021

Raised SGPT indicates liver cell injury. It needs a thorough workup to find the cause.

ASHWANI Reply
December 12, 2021

MY SGOT IS 331 OR SGPT IS 171 PLS SOME ADVISE

Dr. Riaz Reply
December 12, 2021

SGOT/SGPT raised level indicates liver cell injury. You should have viral markers and have ultrasound abdomen. Please keep on checking the liver function tests every three months at least.

vineet Reply
December 13, 2021

SGOT-39
SGPT-66
Drinks occassionally. Is it high? I have gilberts syndrome and little bit high cholestrol
Age-30

Dr. Riaz Reply
December 13, 2021

SGPT is raised, and it indicates liver cell injury. Can you check your gamma GT level? If it is raised, then avoid alcohol.

vineet Reply
December 13, 2021

Ultrasound abdomen is normal

Anurag Gautam Reply
December 17, 2021

Hello Doctor,
I went through with the routine checkup and Below are my reports.
Please advise.

HbA1c 5.7
LDL CHOLESTEROL – DIRECT 173
TOTAL CHOLESTEROL 239
HDL CHOLESTEROL – DIRECT 37
LDL / HDL RATIO 4.7
TC/ HDL CHOLESTEROL RATIO 6.5
BILIRUBIN – TOTAL 1.49
ASPARTATE AMINOTRANSFERASE (SGOT ) 207.9
ALANINE TRANSAMINASE (SGPT) 395.76

Dr. Riaz Reply
December 17, 2021

Your reports are not good. It looks you are not living a healthy life. Your HDL is low, good cholesterol, while LDL is high, which is bad cholesterol. Liver enzymes are raised. Please consult a physician to find the cause of these abnormalities.

Ella Mae Reply
December 19, 2021

Hi Doc! My SGPT is 358.1 and alkaline is 135.7 Before My test , Im having really bad abdominal pain in the center . What to do ?

Dr. Riaz Reply
December 19, 2021

Your SGPT is raised while alkaline phosphatase is in a normal range. I will suggest complete liver function tests and viral markers. You have not mentioned the age.

Chintu Reply
January 3, 2022

Sir my sgot-22.7,sgpt-38, alkaline phospa te-58,total protein-7.83, total cholesterol-199,ldl-141,hdl-53, triglycerides-118, please advise

Dr. Riaz Reply
January 3, 2022

You have not mentioned your age. Your lipid profile looks good. Only cholesterol is the upper limit.

Jeremy Reply
January 4, 2022

39 year old male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?
Thank you

Jeremy Reply
January 4, 2022

39 year old Male
SGOT-31U/L
SGPT-30 U/L
ALP- 97 IU/L
Albumin- 4.6 GM/ DL
Total Protein – 7.4 G/DL
Do you see any concerns?

Dr. Riaz Reply
January 4, 2022

Congratulations, your LFT is normal.

pam Reply
January 12, 2022

MY AST (SGOT) is 58
MY ALT (SGPT) is 115
I am 63 year old female

Dr. Riaz Reply
January 12, 2022

Your liver functions are abnormal. What about total bilirubin?. I will suggest doing complete liver function tests. I hope you are not taking alcohol?. Your enzymes indicate liver cell injury. It needs full workup and consultation with the physician.

Sarfraz khan Reply
January 21, 2022

My sgpt is 124 sgot 165 and ggt 65
Is it serious sir ?

Dr. Riaz Reply
January 21, 2022

Both enzymes are raised. Not good for your health. Please consult some gastroenterologist and have complete work up. Health is wealth.

Mr. Bhushan Reply
February 3, 2022

Hi Dr. Riaz,

I drink 3 times a week heavy (270ml in one sitting) from last 10 years. I have been reading on LFT and so did the test.
My SGOT is 38 (0<30) and SGPT is 95 (0<45) rest stuff are all under normal range.
Can you please advice me further diagnosis.
PS: I am healthy and fit and heavily cut on my drink from last few weeks (sitting once in a week 180-240 ml)

Dr. Riaz Reply
February 3, 2022

Raised SGPT level indicates liver cell injury. SGOT is not specific for liver cell injury as compared to SGPT. I suggest that you quit the alcohol and repeat the liver function test after 3 months. Otherwise, you may develop liver cirrhosis.

Sayan ghosh Reply
February 5, 2022

Hii sir
My bilirubin total 1.42
Sgot 65.14
Sgpt 76.48
I am 21 y old

Dr. Riaz Reply
February 5, 2022

Your SGOT and SGPT are raised, indicating liver cell injury. I hope you are not taking alcohol?. If not then go for hepatic viral profile.

Biswarup Reply
February 21, 2022

Hi Doctor
6 months back I have done full body check up and I have found my Sgpt -150 ,sgot-72 then I did test for hepatitis B&C and it also came negative and then I farther proceed with ultrasound and it came as grade 2 fatty liver and size of the liver was 17.2 .
By that time I was 30 ,hight 164 cm and weight 81 kg.
I controlled my food habits and did regular exercise and now it is showing after 6 months sgpt-72,sgot-48 and other parameters are ok.
How long it will take to come back to normal or any thing to concern and do I need to go for fibro scan

Dr. Riaz Reply
February 21, 2022

If liver cells are insulted by alcohol or anything else, it will take at least 3 months to regenerate. Also, try to take more fruits. In your case, it is 6 months, and still, SGPT is raised, indicating liver cell injury. If it remains elevated, then consult a gastroenterologist (or hepatologist).

Biswarup Reply
February 21, 2022

Forgot to mention my weight is 62 now

Muhammad Imran Reply
February 23, 2022

My daughter is 2.5 years old today she felt pain in stomach when I done her sgpt it’s too high 450 now what I please guide me
Which doctor I need to consult .

Dr. Riaz Reply
February 23, 2022

You should have complete liver function tests (LFT) and an ultrasound abdomen. After workup, consult a pediatrician.

Agyen Brefo Reply
September 28, 2022

Hello dr I’m 35 my lft
S-bilirubin (total ) 9
S-bilirubin conjugated 1
S-Alkaline phosphatase 79
S-g-Glutamyl transferase 35
S-Alt. (Gpt). 122
S-ASt (Got). 55
S-total protein. 75
S-AlBUMIN. 43
Please comment

Dr. Riaz Reply
September 28, 2022

Are you sure the Total bilirubin is 9? Your SGOt/SGPT is raised, which favors liver cell damage. First, clarify the total bilirubin level. Please also check the viral hepatitis profile (HBV, HCV).

Agyen Brefo
September 29, 2022

Yes please the range is 3.42 – 20.5 umol/l after the text the doctor advise is to stop alcohol and I have been taking livolin forte for three since the test

Dr. Riaz
September 29, 2022

Great.

Nikesh Reply
February 24, 2022

hi Dr Riaz,

Could you please comment on this.

Test Name Results Biological Reference
Interval Units Specimen Test Method
SGOT (AST) 32.15 < 35 U/L Serum IFCC without P5P
SGPT (ALT) 53.58 H < 45 U/L Serum IFCC without P5P
Gamma GT (GGT) 39.00 < 55 U/L Serum Enzymatic,Colorimetric
Assay
Uric Acid 7.95 H 3.5 – 7.2 mg/dL Serum Enzymatic Colorimetric
Method

Dr. Riaz Reply
February 24, 2022

In your lab tests, SGPT is slightly raised, and uric acid is also. You need to repeat SGPT/SGOT and uric acid after at least 1 to 3 months. If still raised, you will need medicine for uric acid and a detailed workup for liver function.

Nikesh Reply
February 25, 2022

Thank you Doc. Appreciate so much

Saleem Reply
February 24, 2022

My wife is 37 weeks and 2 days pregnant. She had severe itching problem but now it’s resolved. LFT level on 14.02.2022 SGPT 226 ,SGOT 149, ALP 188 ,GT 44 all others are in normal range. Fasting bile acid test (4.5 umol/l) with in normal range. no symptom of jiaundice. no other symptoms. HAV IgM non reactive, HAV IGg reactive, anti HEV IGg and IgM non reactive, HbsAg non reactive and anti Hcv non reactive. PT 10 sec., APTT, 25 sec.,.INR 0.91. Abdominal ultrasound showed liver has mildly increased echogenicity. After some dietry change and taking hepa merz syrup for 10 days. Repeat LFT on 24.02.2022, the SGPT 77, SGOT 36 and ALP 176 all other are in normal range. Up till now, according to USG, dilivery is normal. I already consulted two gynecologists, one,s advice is normal dilivery and other in favor of inducing dilivery at 38 week due risk of baby stillbirth. With these elevated liver enzyme, can we go for normal dilivery or should induce dilivery at 38 weeks. Suggest some advice.

Dr. Riaz Reply
February 24, 2022

A gynecologist will give a better answer. Your lab reports say that she has hepatitis A infection and is in recovery. Hepatitis E infection is dangerous in pregnancy, but that test is negative. I will suggest That you consult the third gynecologist and see what she says.

Saleem Reply
February 24, 2022

Thank you sir for your quick response. On the basis of these level of elevated enzyme, can we diagonse inertahepatic cholestasis or Acute fatty liver disease?

Dr. Riaz Reply
February 24, 2022

Please see this link; this may be of help.
https://labpedia.net/alkaline-phosphatase-level-alp/
Also, you can see this link for acute fatty liver in pregnancy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538964/

Loess Reply
February 25, 2022

Bonsoir Dr Riaz s’il vous plait j’ai besoin de explications :
Asat/got <40ul/L
Alat/gpt <37ul/L
ALTL 5.5u /L
ASTL 11.7u/L
Crej2 65.7umol/L
Urée 0,5-7,5mmol/L
Créatinine 40-120umol/L

Dr. Riaz Reply
February 25, 2022

GOT/GPT is normal, indicating liver function. Urea/Creatinine gives information about kidney function, which is also in the normal range.

Dr. Riaz Reply
February 25, 2022

Votre SGPT/SGOT, l’urée et la créatinine sont dans la plage normale. Ces tests parlent des fonctions hépatiques et rénales

Vj Reply
March 2, 2022

SGPT 77
SGOT 30
Currently taking Isotretinoin. Is the mild increase in SGPT caused by Isoretinoin?

Vj Reply
March 2, 2022

SGOT 30
SGPT 77
Currently taking Isotretinoin. Is the mild increase caused by Isotretinoin?

Dr. Riaz Reply
March 2, 2022

This medicine is causing damage to your liver that leads to an increase in SGPT level. You can stop this medicine and repeat SGPT/SGOT after 1 to 2 months.

Charles Reply
March 8, 2022

My test result shows SGPT(ALT) 115 IU/L
ALKALINE PHOSPHATASE 44.5 IU/L
GAMMA GT 51 IU/L
Please help interpret

Dr. Riaz Reply
March 8, 2022

SGPT is raised, and Gamma GT is a very mild increase. It indicates liver cell injury. This may be due to some drugs, alcohol, or viral hepatitis. It would be good to check your liver function tests (LFT) and hepatic viral profile.

ash Reply
April 29, 2022

Why should you not use hemolyzed serum for ALT determination?

Dr. Riaz Reply
April 29, 2022

Because RBCs are also the source of ALT.

Randy Baylon Reply
May 18, 2022

I am 43 years old Male my
SGPT is 43
SGOT 23
Kindly advise if there is something to worry about? thank you very much…

Dr. Riaz Reply
May 18, 2022

SGPT is the normal upper limit, and SGOT is normal. I will suggest repeating the test after one month and taking more fruits. At this stage no need to worry.

Randy Reply
May 19, 2022

Thank you very much Dr. Riyaz… more power to you…

Dr. Riaz Reply
May 19, 2022

Thanks.

Mushtaq Reply
May 20, 2022

Hello Dr. Sb,
I am 42 years and my SGPT is 154 . what does it indicate?

Dr. Riaz Reply
May 20, 2022

SGPT is raised, indicating liver cell injury. This is not good for health. Please advise complete liver function test and viral markers (HBV, HCV). It would be better to consult a physician.

Masroor Reply
May 20, 2022

Sir my LFT(6 para) test is
Serum bilirubin is 6.5 total
Serum bilirubin is 4.5 direct
Serum bilirubin is 2.0 indirect
Sgpt(AlT) is 1957
Alkaline phosphate is 259
Gamma GT is 44

Sir it can be normal my niece age is 18 years

Sanjay Reply
June 5, 2022

Hello Dr. Riaz ,

Below are my details is there a issue in liver and is it concerning ?

BILIRUBIN – TOTAL 0.6 mg/dl
BILIRUBIN -DIRECT 0.2 mg/dl
BILIRUBIN (INDIRECT) 0.4 mg/dl
ASPARTATE AMINOTRANSFERASE (SGOT ) 42 U/l
ALANINE TRANSAMINASE (SGPT) 90 U/l
ALKALINE PHOSPHATASE 76 U/L
GAMMA GLUTAMYL TRANSFERASE (GGT) 60 U/l
PROTEIN – TOTAL 7.1 gm/dl
ALBUMIN – SERUM 4.9 gm/dl
SERUM GLOBULIN 2.2 gm/dL
SERUM ALB/GLOBULIN RATIO 2.23

Sanjay Reply
June 5, 2022

My age is 34

Dr. Riaz Reply
June 5, 2022

SGPT and GGT are raised, indicating liver cell injury. I hope you are not taking any form of alcohol or pain killer?. You need to consult a physician.

Sanjay Reply
June 5, 2022

My age is 34

Maris Reply
June 8, 2022

I am 39 years old Female
My SGOT is 213.4 I am currently taking medications and supplements for my liver. After 2 weeks I took another lab exam for my SGOT and SGPT.
Right now my SGOT is 37.2 but my SGPT is high 54.4

Dr. Riaz Reply
June 8, 2022

What was the SGPT the first time that you have not mentioned it? if you repeat the test after two weeks, SGPT may become normal by then?.

Sumi Reply
June 11, 2022

Age-36
Female
SGPT -75
USG report normal
How can I decrease the SGPT level?
Is it serious?
Please suggest some foods help to reduce SGPT.
walking can help?

Sumi Reply
June 11, 2022

I’m 36 years old female
SGPT 75
What I can do to decrease the sgpt?
Please suggest some foods help to reduce SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.

Sumi Reply
June 11, 2022

I’m 36 years old female
SGPT 75
USG report is normal
What I can do to decrease the sgpt?
Please suggest some food help to decrease the SGPT.
Can Walking help?
I took montelukast and levocetirizine every day.

Dr. Riaz Reply
June 11, 2022

This SGPT may be due to medication. If you can afford it, stop this medication for one month and recheck the SGPT. As regards fruits, you can try grapefruit.

Harman Reply
June 14, 2022

Sir my age is 22. I do not consume alcohol
Total bilirubin=3.9
Direct bilirubin = 0.5
SGOT = 106
SGPT = 406
ALP P = 139
I consulted a doctor he advised that it is viral hepatitis with low virulence, no medication is needed. It will get good automatically. Do i need to worry

Dr. Riaz Reply
June 14, 2022

Please get a viral hepatitis profile (HBV, HCV, HAV). No doubt there is an insult to the liver.

Dr. Riaz Reply
June 14, 2022

Please advise viral hepatitis profile (HBV, HCV, HAV). Your LFT shows insult to the liver.

AK Reply
June 14, 2022

Hi
My mother’s Sgot is 16 and Sgot is 6.30, though the values are within the normal range but the Sgot/Sgot ratio is 2.54. Is it a cause of concern? Please advise

Dr. Riaz Reply
June 14, 2022

When SGOT and SGPT are normal, then no need to see the ratio.

GJ Reply
June 28, 2022

Sir, my SGPT – 98, SGOT- 70 All the other values in my liver function test are in normal range. Platelet count is 328 and fasting Glucose is 92. My Lipid profile is also in normal range. Please advice next step

Dr. Riaz Reply
June 28, 2022

Your SGOT/SGPT is raised, indicating liver cell injury. It would help if you had worked up, and I hope you are non-alcoholic. Please check your hepatitis viral profile.

Abhinav Reply
July 15, 2022

sir my mother is 42 and her LFT profile is
BILIRUBIN – TOTAL 0.61 mg/dl
BILIRUBIN -DIRECT 0.18 mg/dl
BILIRUBIN (INDIRECT) 0.43 mg/dl
SGOT – 36 U/l
SGPT-43 U/l
ALKALINE PHOSPHATASE -81U/L
PROTEIN – TOTAL 7.30 g/dl
ALBUMIN – SERUM -4.2 g/dl
SERUM GLOBULIN -3.10 g/dL
and Lipid profile is –
Total cholesterol-192 mg/dl
Triglyceride- 169 mg/dl
HDL- 50 mg/dl
VLDL- 33.8 mg/dl
LDL- 108.2
Non-Hdl-142
LDL/HDL RATIO- 2.16 %
TOTAL/HDL RATIO – 3.84
please advice is there any thing to worry?

Dr. Riaz Reply
July 15, 2022

There is no worry about these results only if you can control her cholesterol, triglycerides, and LDL. While HDL is good. Please manage the fat intake and advise exercise.

Amar Reply
July 16, 2022

Hi.
I did test 2 weeks ago for my job alplication. My sgpt is 51, and sgot 38.
So i need to get some medicine and retake the test. And now my sgpt is 34 and sgot same 38.
Can you please explain what happened to me 2 weeks ago? Im so curious
Thanks

Dr. Riaz Reply
July 16, 2022

SGPT mild raise may be due to intake of pain killers even. So that might be due to some drugs effect. After a few days liver becomes normal.

Anna Reply
August 1, 2022

Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!

Loise Reply
August 1, 2022

Hi, I am 40 year old female. I have SGPT(ALT) 62.5 and SGOT (AST) 29.2. What should I do? How to lower down my SGPT?…Please advise…Thank you!

Dr. Riaz Reply
August 1, 2022

Raised SGPT indicates liver cell injury. Please check your viral profile (HBV, HCV, HAV). Are you taking any medicine or alcohol?
Grapefruit is considered good for the liver.

AARIKA Reply
August 2, 2022

BILIRUBIN, TOTAL 1.01
BILIRUBIN CONJUGATED (DIRECT) 0.36
BILIRUBIN (INDIRECT) 0.65
ALANINE AMINOTRANSFERASE(ALT/SGPT) 63
ASPARTATE AMINOTRANSFERASE(AST/SGOT) 44
ALKALINE PHOSPHATASE 72
PROTEIN, TOTAL 7
ALBUMIN 4.6
A/G RATIO 1.92
Is this normal?

AARIKA Reply
August 2, 2022

My age is 29, Do I need to worry?

Dr. Riaz Reply
August 2, 2022

Your SGPT/SGOT level is mildly raised, indicating liver cell injury. It would be best if you found the cause of liver cell injury. Please check your viral hepatic profile in case of non-alcoholics.

D.priyadarshani Reply
August 5, 2022

Doctor, my husband’s LFT report as follows. Total protein 7.1g/dl
Albumin 4.5 g/dl
Globulin 2.6
Albumin globulin ratio 1.73
Bilirubin total 1.06
AST/SGOT 20.2
ALT/ SGPT 27.6
ALKALINE PHOSPHATASE 85
GGT 70.3
He is 40 years old and over weight. now he follows a diet plan. His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.

Dr. Riaz Reply
August 5, 2022

GGT is not too high. It is an indicator of alcohol intake. I hope he is a non-smoker and non-alcoholic. You can repeat GGT after 1 to 2 months. Let him reduce his weight. If possible, ask him to take more fruits.

D.priyadarshani Reply
August 5, 2022

No doctor. He is non alcoholic and non smoker. But he has blood sugar, pressure and cholesterol. Take medications for that. All values are within reference range. Thank you for your advice.

Sandeep kaur Reply
August 13, 2022

My father age 51 and sgot 115,,sgpt 104.

Dr. Riaz Reply
August 13, 2022

SGOt and SGPT are raised, indicating liver cell injury. Please consult a physician to find out the cause of liver cell damage.

Duhanthi Reply
August 23, 2022

Doctor, my husband’s LFT report as follows. Total protein 7.8g/dl
Albumin 4.8 g/dl
Globulin 2.8
Albumin globulin ratio 1.83
Bilirubin total 1.06
AST/SGOT 22.2
ALT/ SGPT 25
ALKALINE PHOSPHATASE 85
GGT 70.3 U/L
He is 40 years old,non alcoholic and over weight. Take medication for diabetes, pressure and cholesterol. All the report are normal now and he follows a diet plan. Still His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.

Duhanthi Reply
August 23, 2022

Doctor, my husband’s LFT report as follows. Total protein 7.8g/dl
Albumin 4.8 g/dl
Globulin 2.8
Albumin globulin ratio 1.83
Bilirubin total 1.06
AST/SGOT 22.2
ALT/ SGPT 25
ALKALINE PHOSPHATASE 85
GGT 80.3 U/L
He is 40 years old,non alcoholic and over weight. Take medication for diabetes, pressure and cholesterol. All the report are normal now and he follows a diet plan. Still His ggt level seems to be higher than the reference range. Is this a big issue? Please advise.

Dr. Riaz Reply
August 23, 2022

GGT is a very sensitive test. This may be due to medications (drugs). Sometime medication like statin may increase GGT. I think to keep an eye on Liver function tests.

Sintu Kumar Samanta Reply
September 1, 2022

My age is 40. I have done a complete liver function test. My SGOT is 38.60 and SGPT is 80.60. Rest parameters are in the normal range. My SGPT was found normal 5 months back. In the meantime, I have taken some medicines for issues of osteoarthritis. Please advise

Dr. Riaz Reply
September 1, 2022

SGPT is raised, which might be due to medication for osteoarthritis. You need exercise to overcome osteoarthritis changes. Because 40 years is not the age of osteoarthritis changes. Exercise, exercise, and exercise is the best medication for osteoarthritis changes.

Akshit Reply
September 12, 2022

if serum bilirubin total = 1.16 mg/dl ,serum bilirubin (direct) = 0.20 mg/dl & serum bilirubin (indirect) = 0.96 mg/dl
AST/SGOT=20.50 U/L ,ALT/SGPT=17.90 & ALP =136.00 U/L
AGE -19
PLEASE SUGGEST WHAT HAVE TO DO

Akshit Sharma Reply
September 12, 2022

Doctor, my son age 19 has LFT report as follows.
Serum Bilirubin (Total )=1.16 mg/dl
Serum Bilirubin (Direct )= 0.20 mg/dl
Serum Bilirubin (Indirect )-0.96 mg/dl
AST/SGOT =20.50 U/L
ALT/ SGPT =17.90 U/L
ALKALINE PHOSPHATASE ALP= 136.00 U/L
SIR His serum bilirubin (Indirect) and ALP level seems to be higher than the reference range. Is this a big issue? Please advise.

Dr. Riaz Reply
September 12, 2022

These liver function tests are in the normal range. Alkaline phosphatase normal values vary from lab to lab. Indirect bilirubin is not significantly high. Total bilirubin is in the normal range. You can repeat liver function tests after 2 to 3 months.

Vivek Kumar Reply
September 25, 2022

Hello Doctor, My mother’s age is 45 yr, her lever test report as follows.
Serum Bilirubin Total 0.94 mg/dl
Serum Bilirubin Direct 0.63 mg/dl
Serum Bilirubin InDirect 0.31 mg/dl
SGPT 88.5 IU/L
SGOT 80.5 IU/L
Alkaline Phosphatase 69.3 U/L
Total Protein 6.96 gm/dl
Albumin 3.03 gm/dl
Globulin 3.93 gm/dl
Her mouth and tongue and throat is Blistered, unable to eat and drink and she is very weak ,weight about 38 kg, please suggest me what to do ? and is there any things to worry.

Dr. Riaz Reply
September 26, 2022

Your mother’s SGOT and SGPT are raised, indicating chronic liver disease. Please check her viral hepatitis B and C. There is a possibility of viral hepatitis.

Simon Brown Reply
October 12, 2022

Dear Dr. Riaz,
I really appreciate you helping out everyone. I am male 44 years old and have been doing 48 to 60 hours fasts to lose weight. I have lost around 10 kg, however, I am still overweight. Otherwise I am not suffering from any problems that I know of.

I did a Liver profile and following are my readings:

Serum Total Bilirubin: 1.3
Serum Direct Bilirubin: 0.4
S.Indirect Bilirubin: 0.9
Serum Gamma GT: 27
SGPT (ALT): 66
Serum Alk phosphatase: 124
SGOT (AST): 35

Please advise, thank you!

Dr. Riaz Reply
October 12, 2022

Thanks for the remarks. Your SGPT is slightly raised, which indicates liver cell injury. If you are taking pain killer, that may also raise SGPT. Repeat SGPT/SGOT after one month. As regards being overweight, keep yourself active. You can try intermittent fasting. Control sugary things and carbohydrates.

Dr. Riaz Reply
October 12, 2022

Please see the link:
https://labpedia.net/how-to-control-weight/

Debarati biswas Reply
October 26, 2022

I am 30 week pregnant..I am suffering extreme itching all over the body..My sgot level 218 and my sgpt level 416..Sir Please advice me..I am suffering a lot..

Dr. Riaz Reply
October 26, 2022

Sometimes the itching is part of pregnancy.
Please check your bilirubin and alkaline phosphatase levels.
Please read this link, this may help you.
https://www.healthline.com/health/pregnancy/itching-during-pregnancy

Katherine Reply
October 31, 2022

Hi Doctor
I am 26 yrs old female
My SGOT 20 U/L
SGPT 45 U/L
GGT 50 U/L
For medications record, I was taking Mefenamic acid to treat my sore throat for one week.
may I have your advice on my liver profile?
may i know how to lower the liver enzymes?

Saranraj Reply
November 1, 2022

Hi Doctor
I’m 34 Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet for 15 days(3 times in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
My Report taken on 23.10.22 :
LIVER FUNCTION TEST with GGT
SERUM G G T 210.5 U/L
SERUM SGOT 900 U/L
SERUM SGPT 1549 U/L
SERUM BILIRUBIN TOTAL :6.71 mg/dl
SERUM BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
SERUM ( Hepatitis B ) Non reactive 0.36
SERUM ANTI HCV (C VIRUS) Nonreactive (0.09)

Pls suggest Doctor ,Can I continue the Liv 52 tablet another one week?

Saranraj Reply
November 1, 2022

Hi Doctor
I’m 34 Years Male Affected with Jaundice and Taken the below test report on 23rd October and met a General Doctor . He advised to take Liv 52 Tablet for 15 days(3 times in a day) . I am not facing any Pain apart from lighter body tired. Kindly suggest me what to do next sir?
My Report taken on 23.10.22 :
LIVER FUNCTION TEST with GGT
SERUM G G T 210.5 U/L
SERUM SGOT 900 U/L
SERUM SGPT 1549 U/L
SERUM BILIRUBIN TOTAL :6.71 mg/dl
SERUM BILIRUBIN DIRECT: 5.23 mg/dl SERUM BILIRUBIN INDIRECT : 1.48 mg/dl
SERUM ( Hepatitis B ) Non reactive 0.36
SERUM ANTI HCV (C VIRUS) Nonreactive (0.09)

Pls suggest Doctor ,Can I continue the Liv 52 tablet another one week? Nothing to worry right?

Abhinav Reply
November 12, 2022

sir my mother is 42 and her LFT profile is
BILIRUBIN – TOTAL 0.35 mg/dl
BILIRUBIN -DIRECT 0.17 mg/dl
BILIRUBIN (INDIRECT) 0.18 mg/dl
SGOT – 39 U/l
SGPT-50 U/l
ALKALINE PHOSPHATASE -80U/L
PROTEIN – TOTAL 7.40 g/dl
ALBUMIN – SERUM -4.4 g/dl
SERUM GLOBULIN -3.00 g/dL
and Lipid profile is –
Total cholesterol-183 mg/dl
Triglyceride- 198 mg/dl
HDL- 58 mg/dl
VLDL- 39.6 mg/dl
LDL- 85.4
Non-Hdl-125
LDL/HDL RATIO- 1.47 %
TOTAL/HDL RATIO – 3.16
please advice is there any thing to worry?

Dr. Riaz Reply
November 12, 2022

SGPT is raised, which indicates liver cell injury. This may be due to medications like a pain killers. Triglycerides are also raised. She needs to take a low-fat diet. Please repeat the liver function test after one month.

Kumar Reply
November 21, 2022

Good Eve Sir ,
My Name is Kumar ,age is 34 and my LFT Results is below
SERUM GGT – 50.4 U/L , SERUM SGOT -148 U/L , SERUM SGPT -264 U/L
SERUM ALKALINE PHOSPATE -88 U/L.
SERUM BILIRUBIN TOTAL – 2.93 mg/dl (Direct -1.96 & Indirect-0.99)
SERUM PROTEIN TOTAL – 7.3 gm/dl
SERUM ALBUMIN SERUM – 4.3 g/dl
SERUM GLOBULIN – 3.0 gm/dl & SERUM A/G RATIO – 1.4
* URINE COMPLETE :
URINE Colour -Light Yellow ,URINE PH-6.5 ,
Urine Specific Gravity -1.004 .
Urine (Protein,Keton &Glucose)- Negative
Urine Urobilinogen -Normal
Urine (Bilirubin &Nitrite)-Negative
Urine (RBC,WBC,YEAST CELLS ,Bacteria,Cast)-0.0

Please advise Doctor….Thank you in advance

Dr. Riaz Reply
November 21, 2022

Your SGPT/SGOT is raised, indicating liver cell injury. I hope you are not taking alcohol. Please provide me with more history.

Kumar Reply
December 1, 2022

Dear Sir ,
Thank you for your reply ! Regarding My alcohol usage – I am a social drinker & I used to have alcohol once in a month only , but in last 6 months I used to have thrice a week due to work pressure . Now for past 1 month I am not using alcohol. Will it be a reason??

* In between of this last 6 months I used to follow my own diet plan ( I Was skipped daily breakfast 4 times in a week , used to have cooked vegtable and liite curd rice at noon on every day and in Night I used to have rasam rice and curd rice on daily basis ). Will it be a reason ?

My USG Report – ABDOMEN & PELVIS
LIVER – Liver is normal in size (measures-14cm) & shows normal echotexture , No focal liver lesion .No Intra hepatic biliary radical dilatation seen.
GALL BLADDER – Is adequately distended.No calculus or cholecystitis seen
PANCREAS – Appears normal in size and shows uniform echo texture.The pancreatic duct is normal .No calcifications are seen
SPLEEN – Appears normal in size and it shows echo texture. It mesures 11.9 cm in long axis.
RIGHT KIDNEY – Right Kidney measures – 10.4 * 3.9cm
The shape ,size and contour of right kidney appears normal.
Cortico medullary differentiation is within normal. No evidence of pelvicalyceal dilatation.No calculi seen.
LEFT KIDNEY – Left Kidney measures -10.4 * 4.8cm
The shape ,size and contour of left kidney appears normal.
Cortico medullary differentiation is within normal. No evidence of pelvicalyceal dilatation.No calculi seen.
URINAY BLADDER – Is Normal Contour .No Intra Luminal echoes are seen
PROSTATE – Prostate appears normal ,Measures -2.3*2.5*3cms (Vol-9cc)
RIGHT ILIAC FOSSA – No Focal fuid collections seen
No Evidence of herina seen in anterior abdominal wall.

PLS ADVICE DOCTOR . I AM WAITING FOR YOUR REPLY

Dr. Riaz Reply
December 1, 2022

I think you are doing good. Once a month social drink will not damage your system, particularly the liver. This is not advisable to skip breakfast. The best would be to take 2 to 4 glasses of water on an empty stomach, then after 30 minutes to take breakfast.

Mahabaleshappa Reply
November 22, 2022

Good noon sir
My self mahabaleshappa .k
My sgot 200
Sgpt 500
Billirubin total 6.03
Billirubin direct 5.02
Bilirubin indirect 1.01
Day by day increasing nd decreasing both are happing sir

Dr. Riaz Reply
November 22, 2022

Your liver functions are disturbed. Please check your viral hepatitis profile (HBV, HCV, and HAV).

Nishad Reply
November 22, 2022

Sir i am 44 yrs MaleHeight = 5.10 ft:inches 88 kg weight & Regular use of Alcohol intake ..since last 12yrs | Take healthy diet + regular execerise (225 heart points/week) as per Google Fit app
Recently done Annual Health Check, and as per ultrasound Liver measures = 12.90cm & both lobes show Grade 2 fatty changes (Grade 2 fatty liver)
however liver parameters show in report as normal :
Total Bilirubin = 0.306 mg/dl
Direct Bilirubin = 0.12
Indirect Bilirubin = 0.19
SGPT/ALT = 20.30
Creatinine = 0.80
All other parameters including cholestrol are Normal. Kidneys Normal, Echo Cardio Normal
Sonography Test Impressions :
Grade 2 fatty liver
Mild Splenomegaly

Sir, Is Grade 2 fatty liver re-versible ?? If yes then, how much time it will take to reverse liver health to normal ?
Is there any indication of liver damage as per above parameters ?
Kindly provide your valuable feed back . Thanks much.

Dr. Riaz Reply
November 22, 2022

No doubt that liver functions are normal, but due to alcohol use, fatty changes in the liver have started. That will leads to cirrhosis of the liver, which is not a reversible change. If you stop taking alcohol now, there will definitely be an improvement in liver changes.

Nishad Reply
November 22, 2022

Thank you Riaz sir for your guidance..

Till how much time i need to cease/stop alcohol intake in order to completely reverse grade 2 fatty changes ? 4 weeks / 3months / 9 months ? Will not have alcohol at all during this time.

Can in-take of extract of Moringa Oleifera (Drumstick) + Acacia Arabica (Babool) cause fatty liver / heptacellular changes in Liver ? I take this combination of extract in warm water daily once for knee joints .

Will go for US (UltraSound) post confirmed period but may not be able to completely avoid alcohol in the future !

Thanks in advance.

Dr. Riaz Reply
November 23, 2022

I think stopping alcohol is the only answer. If you start again, then again liver will be damaged. If you want alcohol, try having a social drink once a week or a month.

haslian Reply
November 28, 2022

Hello Dr. Riaz,

I have had hepatitis A for 3 months, my bilirubin has went down to 8.4 mg/dL from its peak at 15.5 mg/dL. However my SGOT went back up from 44 to 59 U/L (previously peaked at 192 U/L), and the same with my SGPT, it went back up from 39 to 83 U/L (previously peaked at 755 U/L). Is it normal to have fluctuation during the recovery phase?

Dr. Riaz Reply
November 29, 2022

Hepatitis A is a self-limiting disease. SGOT/SGPT level may fluctuate, and it should become normal when the bilirubin level is normal.

Tasbihullah Reply
December 10, 2022

Sir my 2 years daughter ALT is 691 microliter with orange red Urine what I should do further

Dr. Riaz Reply
December 12, 2022

You need to do a complete liver function test with a viral hepatitis profile (HBV, HCV, HAV).

Dr. Riaz Reply
December 12, 2022

Please send me complete liver function tests and viral hepatitis (HBV, HCV, HAV) profiles.

Manu Reply
December 26, 2022

I am having sgpt 73 and sgot 42 all other liver functions are normal.Please advice some remedy

Dr. Riaz Reply
December 26, 2022

Please check your viral hepatitis profile (HBV, HCV). Please let me know the GGT (gamma GT) level. I hope you are not taking pain killer medication.

Oliver Reply
January 2, 2023

I have SGPT/ALT 10.6 mmo/L, please advice

Dr. Riaz Reply
January 3, 2023

This is in the normal range. No need to worry.

Joyvic Reply
January 8, 2023

Hi
My sgpt is 68
Sgot 37
Is it dangerous?
What should I prevent?
🙏

Dr. Riaz Reply
January 9, 2023

SGPT is raised, and it indicates liver cell injury. Please check your viral hepatitis profile (HBV, HCV). I hope you are not taking painkillers or any other drinks.

Nishad Reply
January 10, 2023

Riaz sir,

I had posted on this forum as on 22nd Nov 2022 – Alcoholic Fatty Liver (Grade 2) .
As per that report of NOV 2022 :
Total Bilirubin = 0.306 mg/dl
Direct Bilirubin = 0.12
Indirect Bilirubin = 0.19
SGPT/ALT = 20.30
Creatinine = 0.80
All other parameters including cholestrol are Normal. Kidneys Normal, Echo Cardio Normal
Sonography Test Impressions :
Grade 2 fatty liver
Mild Splenomegaly
—————-
Yesterday got my LFT + USG Abdomen done : (No change in diet intake + 1 hr daily excercise)
> Completely abstained from any form of alcohol
As per recent report ie 10th Jan 2023 , Grade 2 has changed to Grade 1 now :
Total Protein = 6.77 gm/dl
Albumin,Serum = 4.62 gm/dl
Globulin = 2.15 (bold in report)
A/G Ratio = 2.15
SGOT (AST) = 16.98
SGPT (ALT) = 13.20
Alkaline Phosphatase = 61.27
Total Bilirubin = 0.47
Conjugated Bilirubin(Direct) = 0.23
Un-Conjugated Bilirubin(Indirect) = 0.24
Gamma GT = 24.15 IU/L
In USG report : “Liver is normal in size,outline and shows mild diffuse increased parenchymal echogenicity, suggestive of Grade 1 Fatty Changes. No focal lesson is seen. IHBRs are not dilated.
Spleen size is normal & outline . (In Nov2022 : Mild Slenogemaly

Recent report Impression feedback:
> Grade 1 Hepatic Steatosis
> Splenic Cyst

Dr. Riaz Reply
January 11, 2023

Your liver functions are normal. The liver fatty change will improve with time. The splenic cyst needs to be further work-up. Please take more fruits which will help liver to become normal.
Take plenty of water and liquids.

Nishad Reply
January 11, 2023

Thanks much Riaz sir.

Kindly suggest importance of Globulin = 2.15 (bold in report) value when Liver function is normal ?

Dr. Riaz Reply
January 11, 2023

Globulin level is normal. No need to worry.

Abhinav Reply
January 13, 2023

Hello Dr. Riaz,
My mom’s angiography report shows Insignificant CAD. Do i need to worry?

Abhinav Reply
January 15, 2023

sir my mother is 42 and her LFT profile is
BILIRUBIN – TOTAL 0.4 mg/dl
BILIRUBIN -DIRECT 0.2 mg/dl
BILIRUBIN (INDIRECT) 0.2 mg/dl
SGOT – 65.2 U/l
SGPT-95.1 U/l
ALKALINE PHOSPHATASE -129.3 U/L
PROTEIN – TOTAL 7.2 g/dl
ALBUMIN – 4.3 g/dl
GLOBULIN -2.90 g/dL
GGT -241.1 U/L
HBsAg – Non reactive
HCV – Non-reactive
Do i need to worry?

Abhinav Reply
January 15, 2023

sir my mother is 42 and her LFT profile is
BILIRUBIN – TOTAL 0.4 mg/dl
BILIRUBIN -DIRECT 0.2 mg/dl
BILIRUBIN (INDIRECT) 0.2 mg/dl
SGOT – 65.2 U/l
SGPT-95.1 U/l
ALKALINE PHOSPHATASE -129.3 U/L
PROTEIN – TOTAL 7.2 g/dl
ALBUMIN – 4.3 g/dl
GLOBULIN -2.90 g/dL
GGT -241.1 U/L
HBsAg – Non reactive
HCV – Non-reactive
Do i need to worry?

Dr. Riaz Reply
January 16, 2023

SGOT/SGPT is raised, indicating liver cell injury. I hope she is not taking pain killer. She needs consultation with a gastroenterologist. I will recommend doing an ultrasound abdomen.

Abhinav Reply
January 16, 2023

Ultrasound abdomen shows grade 1 fatty liver changes everything else is normal. She got discharged last sunday and on medication like dollo 650 for 3-4 days after discharge.

Kumar Reply
February 18, 2023

Hello Doctor good evening, After my jaundice recovery (3 months) I feel itching in both the lower legs at night times . Pls suggest me a solution Doctor.

Abu bakkar Reply
February 28, 2023

Actually I am fontan patient . I underwent four heart surgeries. 2 months ago I was diagnosed with Hepatitis A 7.9 and Hepatitis E was 1.9. 2 months ago my sgpt reached to 1500 and bilirubin was 23 . last week ago I had liver function test my sgpt was 65 and after 1 week i.e today I again had a liver function test . My sgpt is 81 . slightly increase in sgpt

Dr. Riaz Reply
February 28, 2023

Please check your HCV infection. There is fluctuation in HCV infection. If negative, then take more fruits.

Krizzy Reply
March 1, 2023

Sgot 33, sgpt 51, ggt 46 (female, no other symptoms encountered)

Krizzy Reply
March 1, 2023

Had taken oral contraceptives for almost 2 months

Dr. Riaz Reply
March 1, 2023

There is a slight increase in the SGPT. Please check your viral profile. If negative, take more fruits and check SGPT/SGOT after one month. Oral contraceptives may be the cause.

Madhu Reply
March 30, 2023

2 weeks ago
Total Bilirubin: 1.84
Direct Bilirubin: 0.36
Indirect Bilirubin: 1.48
SGOT: 75
SGPT: 90
ALP: 101.80
Total Proteins: 8.54
Albumin: 5.3
Globulin: 3.1
A/G ratio: 1.7

Today
Total Bilirubin: 3.2
Direct Bilirubin: 1.0
Indirect Bilirubin: 2.2
SGOT: 27
SGPT: 30
ALP: 112
Total Proteins: 7.1
Albumin: 3.9
Globulin: 3.2
A/G ratio: 1.2

I trusts my doctor

Just checking
Bilirubin values are increased but SGOT, SGPT and ALP are normal
As per doctor nothing to wrong and not provided any meditation. Some people have Bilirubin values are high

Please suggest if any

Dr. Riaz Reply
March 30, 2023

There is increased indirect bilirubin. That may be due to Gilbert syndrome, where treatment is not needed. But please check your Liver function tests after 2 to 3 months.
In Golbert syndrome, SGOT/SGPT is always normal.

Raj Reply
May 3, 2023

Total Bilirubin: 1.30
Direct Bilirubin: 0.60
Indirect Bilirubin: 1.30
ASAT; 56 U/L
ALAT: 110 U/L
ALP: 115 U/L

I have grade 1 fatty liver and fibro scan shows 4.4.

Please guide me sir. This is normal ?

Dr. Riaz Reply
May 9, 2023

ASAT/ALAT is raised, indicating liver cell injury. I hope you are not taking alcohol. Try more fruits and their juices.

Dr. Riaz Reply
May 9, 2023

AST/ALT is raised, indicating liver cell injury. I ope you are not taking alcohol. Please take more fresh fruits and their juices.

Amar Reply
May 8, 2023

SGPT – 45.8
SGOT – 35.0

I am 38 years male and taking lipiez 20 MG and concure 2.5 everyday. Is this normal range ?

Dr. Riaz Reply
May 9, 2023

Statin mostly cause liver enzyme abnormality. SGPT is in the upper normal range. Please stop statins for one month and then check liver enzymes. Most likely these will be in the normal range.

Amar Reply
May 10, 2023

Sir,
I have 40% blockage in my heart so not able to Statin. Is there any alternate way available to improve SGPT ?

Dr. Riaz Reply
May 11, 2023

Cardiologists can advise a milder form of statin like Ruvastatin 5 mg.

joseph Reply
June 1, 2023

my 3 year old kid had Entrovrius and high fever on 5/13-14. SGPT was 146. 5/15 fever was gone. On 5/16 SGPT rised to 210. The doctor let us out of Hospital on 5/17 since the fever is gone and told us to repeate the SGPT test within a month. Should I be worried? The SGPT didn’t drop when we were let go of the Hospital.

Dr. Riaz Reply
June 1, 2023

I think your physician is right. Please repeat SGPT after one month. Meanwhile check his viral profile (HBV, HCV, and HAV).

Dony Reply
June 2, 2023

Am Having Hepatitis B +ve and result is as below.

Bilirubin: 1.80
ALT/SGPT : 1,163.20
SGOT/AST : 433.00
GGT : 153

Usually How many days it takes to get it normal.

Dr. Riaz Reply
June 2, 2023

Hepatitis B can be treated. I think you need the treatment for HBV. After start of the treatment may take few weeks to become normal.

Asad Reply
June 14, 2023

I recently noticed hypertension and I consulted internal medicine doctor. He gave medicine for high BP to be taken every day morning “coveram”. Further, he advised some tests like Alt (GPT), Electrloytes, BUN, cholesterol, creatinine, triglycerides, TSH3. All tests were normal except Alt (GPT) which is 73. Advise please.

Dr. Riaz Reply
June 14, 2023

Please check your gamma-GT and alkaline phosphatase. Sometime medicines cause injury to liver cells and this may be due to Coveram.

Rabbi Reply
June 19, 2023

I had hepatitis A. After 6 week of diagnosis my sgpt is 55. is it ok?

Rabbi Reply
June 19, 2023

I had hepatitis A. After 6 week(44 days) of diagnosis my sgpt is 55. is it ok that I am recovering so slowly?

Rabbi Reply
June 19, 2023

I had hepatitis A. After 6 week of diagnosis my sgpt is 55. is it ok to recover this slow?

Dr. Riaz Reply
June 19, 2023

Viral hepatitis A has no chronicity. Mostly patients completely recovered. You will have a complete recovery. Please repeat SGPT/SGOT and bilirubin level every month.

UMAIR Reply
July 3, 2023

Sir my LFT test
bilirubin is 0.4 total
bilirubin is 0.1 direct
bilirubin is 0.3 indirect
Sgpt(AlT) is 48
Sgot (AST) 31
Alkaline phosphatase 64
Gamma GT is 41
Albumim 5.0
Globulins 2.9
Total Protein 7.9
A:G Ratio 1.7

Sir it can be normal my age is 23 years
LFT normal? PLZ HELP ME

Dr. Riaz Reply
July 3, 2023

Please repeat SGPT/SGOT after one month. At present I will say normal liver function test. Ignore SGPT at this point. After repeat test, let me know the result.

Auyal Mallik Reply
July 5, 2023

I am having S. Alt (SGPT) 115 U/L and sgot 42 all other liver functions are normal.Please advice some remedy

Dr. Riaz Reply
July 5, 2023

Raised SGPT indicates liver cells injury. I hope you are not taking alcohol. Please check your viral hepatitis profile (HBV, HCV). Please take more fruits and check your liver function after one month.

Krishna Sharma Reply
August 7, 2023

Please advise on ALT issue:

ALT 66
AST 29
AKLALINE PHOSPHATE 104
BILIRUBIN (TOTAL) 0.5
GLOBULIN 3.2
ALBUMIN 4.4
PROTEIN (TOTAL) 7.6
CALCIUM 9.5
CARBON DIOXIXE 22
CHLORIDE 104
POTASSIUM 4.4
SODIUM 137
EGFR 97
CREATINE 1.0
UREA NITROGEN (BUN) 17
GLUCOSE (FASTING) 91

Dr. Riaz Reply
August 8, 2023

Your ALT (SGPT) is raised which indicates liver cell injury. Please take more fruits and juices, repeat ALT after one month. I hope you are not eating pain killer?

Umair Ahmed Reply
August 17, 2023

Sir my LFT test again report
bilirubin is 0.3 total
bilirubin is 0.1 direct
bilirubin is 0.2 indirect
Sgpt(AlT) is 45
Sgot (AST) 28
Alkaline phosphatase 66
Gamma GT is 38
Albumim 5.1
Globulins 2.6
Total Protein 7.7
A:G Ratio 2.0
The report is fine?
I have to get Visa Gamca medical done.PLZ HELP ME
Best Regard,
Umair.

Dr. Riaz Reply
August 17, 2023

Your SGPT is upper limit of normal. Please avoid pain killer and take more fruits and fresh juices. Repeat after one month. Most likely they may ignore it. What about hepatitis viral profile (HBV, HCV)?

Umair Ahmed Reply
August 18, 2023

UMAIR Reply
July 3, 2023
Sir my LFT test
bilirubin is 0.4 total
bilirubin is 0.1 direct
bilirubin is 0.3 indirect
Sgpt(AlT) is 48
Sgot (AST) 31
Alkaline phosphatase 64
Gamma GT is 41
Albumim 5.0
Globulins 2.9
Total Protein 7.9
A:G Ratio 1.7

Sir it can be normal my age is 23 years
LFT normal? PLZ HELP ME

Dr. Riaz Reply
July 3, 2023
Please repeat SGPT/SGOT after one month. At present I will say normal liver function test. Ignore SGPT at this point. After repeat test, let me know the result.

Umair Ahmed Reply
August 17, 2023
Sir my LFT test again report
bilirubin is 0.3 total
bilirubin is 0.1 direct
bilirubin is 0.2 indirect
Sgpt(AlT) is 45
Sgot (AST) 28
Alkaline phosphatase 66
Gamma GT is 38
Albumim 5.1
Globulins 2.6
Total Protein 7.7
A:G Ratio 2.0
The report is fine?
I have to get Visa Gamca medical done.PLZ HELP ME
Best Regard,
Umair.

Dr. Riaz Reply
August 17, 2023
Your SGPT is upper limit of normal. Please avoid pain killer and take more fruits and fresh juices. Repeat after one month. Most likely they may ignore it. What about hepatitis viral profile (HBV, HCV)?

NEW REPORT 16-Aug-2023
ALL MEDICAL TESTS REPORT
LIVER FUNCTION TESTS *
Bilirubin Total 0.5
ALAT (SGPT) 52.5
ASAT (SGOT) 29.4
ANTI HCV (ECLIA)
Patient’s Value 0.081
Cut of Value 1.000
“Non-Reactive”
Conclusion

HBS AG (ECLIA)
Patient’s Value 0.489
Cut of Value 1.000
“Non-Reactive”
Conclusion
TPHA/TPPA ( ECLIA ) **

Patient’s Value 0.116

Cut of Value 1.000
“Non-Reactive”
Conclusion
ERYTHROCYTES SEDIMENTATION RATE

ESR ( Westergren ) 12

VDRL-RPR ( QUALITATIVE )
“Non-Reactive”
VDRL -RPR ( Antec )

NOTE: HBsAg and Anti HCV are “Non-Reactive” on immunochromatography as well (by Acu -check)
* Performed on Roche HITACHI (COBAS c311) Automatic Chemistry Analyzer
** Performed on Automatic Immunology Analyzer ( COBAS e411 )

Faizan Reply
September 16, 2023

My SGPT is 132
SGOT is 37

Heb b and c negative

Dr. Riaz Reply
September 16, 2023

That is good for you. SGPT is in the normal range. You can repeat liver function tests after one month.

Thiyagu Reply
November 21, 2023

Hello Doctor,

Kindly please help me as my little kid 1yr who was tested and given with the below test results, tell me what is his problem,

LFT:
Total Bilirubin 0.24
Conjugated (D.Bilirubin) 0.10
UnConjugated (I.D.Bilirubin) 0.14
Total proteins 6.8
Albumin 4.4
Globulin 2.4
A/G Ratio: 1.83
SGOT: 168
S.G.P.T: 210
Alkaline phosphatase 338
GGT : 22

Free thyroid profile CLIA
Sample type : Serum

FT3: 4.03
FT4: 19.3
TSH: 1.90
CPK: 209.8

Serum total calcium: 10.16
Serum Creatinine : 0.3
Serum urea: 24.6
Serum sodium: 139.1
Serum potassium: 4.75
Serum chloride: 106.4
Vitamin D: 30.3

Dr. Riaz Reply
November 21, 2023

Alkaline phosphatase is mostly raised in the children. Only SGOT/SGPT are raised indicating liver cell injury. Urea/creatinine are normal. other tests look normal, although you have not written the units. For raised SGOT/SGPT, please advise viral profile for hepatotropic viruses (HBV, HCV).

Binai Reply
December 23, 2023

Male
BLOOD SUGAR (RBS) :117.9
TOTAL CHOLESTEROL : 197.8
TRIGLYCERIDES : 148.5
HDL CHOLESTEROL : 45.1
LDL CHOLESTEROL (DIRECT) 122.2
UREA(BUN) 32.86
CREATININE 1.32
URIC ACID 8.7

Total Protein 8.7
Albumin 5.4
Globulin 3.3
Total Bilirubin 0.82
Direct Bilirubin 0.23
Indirect Bilirubin 0.59
SGPT/ALT 73.3
SGOT/AST 29.9
Alkaline Phosphatase 99.2
Gamma GT 33
AG Ratio 1.6:1
CALCIUM 10.2

RBC COUNT 5.51
HEMOGLOBIN 15.4
HCT 48.3
MCV 87.7
MCH 28
MCHC 31.9
RDW-CV 14
RDW-SD 44.1
WBC 8.02
NEU 50
LYM 40
MON 6
EOS 4
BAS 0
GRA# 3.96
LYM# 2.98
PLT 294
Erythrocyte sedimentation Rate (ESR) 5
IS THIS FINE?

Dr. Riaz Reply
December 24, 2023

Your blood reports show few abnormalities:
1. Cholesterol is borderline.
2. Triglycerides are mildly raised.
3.LDL also mildly elevated.
4. Creatinine is upper limit.
5. SGPT is also raised.
Please consult good physician to sort out these abnormalities.

MJ Reply
January 22, 2024

Hi Dr. Riaz,

I am 30 yr old female taking PTU for hyperthyroidism, my SGPT is 416 but my FT4 now is within normal at 12.70, TSH is low at 0.007. Please advise what to do about my SGPT. Thank you

Dr. Riaz Reply
January 23, 2024

SGPT is too high. You have to talk to your endocrinologist/primary physician to change the medicine.

Wini Reply
January 26, 2024

Bilirubin-Total 0.54 mg/dL 0.2-1.2 Diazonium Salt
Bilirubin-Direct 0.25 mg/dL 0.0-0.5 Diazo Reaction
Bilirubin-Indirect 0.29 mg/dL 0 – 0.8 Calculated
Protein, Total 8.14 g/dL 6.4 – 8.3 Biuret, End Point
Albumin 4.62 g/dL 3.5-5.0 Bromcresol Green
Globulin 3.5 g/dl 1.8 – 3.6 Calculated
A/G Ratio 1.31 Ratio Calculated
Aspartate Transaminase (SGOT) 44 U/L 11 – 34 NADH (Without P-5-P)
Alanine Transaminase (SGPT) 46 U/L 0-34 NADH (Without P-5-P)
SGOT/SGPT 0.96 Ratio Calculated
Alkaline Phosphatase 83 U/L 40-150 Para-Nitrophenyl
Phosphate
Gamma Glutamyltransferase (GGT) 63 U/L 9 – 38 L-G-G-3-C-4-N Substrate

Dr. Riaz Reply
January 26, 2024

Please see my remarks.

Wini Reply
January 26, 2024

Hello doctor,
Kindly help me to know whether it is normal and nothing serious to worry

Bilirubin-Total 0.54 mg/dL 0.2-1.2 Diazonium Salt
Bilirubin-Direct 0.25 mg/dL 0.0-0.5 Diazo Reaction
Bilirubin-Indirect 0.29 mg/dL 0 – 0.8 Calculated
Protein, Total 8.14 g/dL 6.4 – 8.3 Biuret, End Point
Albumin 4.62 g/dL 3.5-5.0 Bromcresol Green
Globulin 3.5 g/dl 1.8 – 3.6 Calculated
A/G Ratio 1.31 Ratio Calculated
Aspartate Transaminase (SGOT) 44 U/L 11 – 34 NADH (Without P-5-P)
Alanine Transaminase (SGPT) 46 U/L 0-34 NADH (Without P-5-P)
SGOT/SGPT 0.96 Ratio Calculated
Alkaline Phosphatase 83 U/L 40-150 Para-Nitrophenyl
Phosphate
Gamma Glutamyltransferase (GGT) 63 U/L 9 – 38 L-G-G-3-C-4-N Substrate

Dr. Riaz Reply
January 26, 2024

Mostly your parameters are normal except SGOT/SGPT and GGT which are upper normal limit. So please repeat SGOT/SGPT and GGT after one month. Meanwhile take more fruits.

Troy Reply
January 27, 2024

Hi Doctor,
My SGOT/AST is 47 and SGPT/ALT is 105.

I’m 51 years. Male

Is this alarming?

Thank you

Dr. Riaz Reply
January 27, 2024

Your SGPT is raised and is alarming. It needs further workup to rule out any issue in the liver like ultrasound abdomen. Please also check your GGT.

S Reply
May 28, 2024

Dr Riaz, my mother aged 67 yrs, has SGPT 13 U/L and SGOT is 22 U/L. Is this normal?

Dr. Riaz Reply
May 28, 2024

SGOT/SGPT are in the normal range.

Jisna Reply
July 26, 2024

Jisna
I tested sgpt.it was 43u/l in May, 30 in July Ist week and now 37. Other parameters as ast, bilirubin, Alp, and others in lft appear normal. I take alcohol, but now am cutting it down. Kindly advise what is to be done. Is the sgpt swings normal? regards
Jisna

Dr. Riaz Reply
July 27, 2024

You should do SGOT/SGPT and Gamma GT. That will tell the alcohol effect on your body systems. Alcohol mostly damages the liver first and then cardiovascular system. Actually, alcohol give empty calories.

Jisna Reply
July 27, 2024

SGOT is 24u/l. SGPT is 37. I was worried about the SGPT swings . kindly advise. Thanking in advance

Dr. Riaz Reply
July 27, 2024

S Typhi H = 1:160 indicates past infection or vaccination. For carriers you have to do Vi-antigen. If that is positive, then those carriers need long term antibiotics or cholecystectomy.

Dr. Riaz Reply
July 27, 2024

Your SGOT/SGPT are in the normal range. No need to worry. Check your gamma-GT, that is good marker for alcohol intake.

Jisna Reply
July 27, 2024

Thank you much doctor. You have been very helpful and kind. Regards.

Jisna Reply
August 20, 2024

…

Jisna Reply
August 20, 2024

My wife blood check up shot is 39 and sgpt is 59. Kindly advise

Jisna Reply
August 20, 2024

Sir, I meant sgot is 39 and sgpt is 59.

Abhishek Reply
November 6, 2024

Hello sir my age is 28 ..
I randomly tested for lfts my total billirubin 1.22 sgpt 34.43 ,sgot 72.55 and alp 93 ..
After 18 days I tested again at that time my total billirubin was 1.00 sgpt 63 and sgot 43.23 and alp 55..
I am going through alot of stress.. is there is any problem sir I am not a drinker .. my BMI is 22.5 .. I smoked some time .. and at that time I slept only 4-5 hours in a night.

Dr. Riaz Reply
November 8, 2024

In first LFT Only SGOT was raised. And again, SGOT was mildly raised. Please take more fruits and again check LFT after one month. I hope you are not taking pain killers.

Abhishek Reply
November 6, 2024

I drink a faluda before the night of my second test.

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