Mycosis Fungoides

This is Cutaneous T- cell Lymphoma. There is proliferation of CD4 + cells.

Clinically it is classified into :

Premycotic stage : 

1. This is inflammatory condition. 
2. Skin is erythematous, scaly, and pruritus.
3. This gives picturs of chronic nonspecific dermatitis.

Mycotic stage:

1. There is appearance of inflammatory plaques.
2. There is polymorphous inflammatory infiltrate in the dermis.
3. There are atypical histiocytes.
4. Pautrier microabscess are seen which is infiltration of epidermis by the histiocytes.

Tumorous stage:

1. Now atypical histiocytes predominates.
2. In late stage lymph nodes are involved.
3. There is also involvement of the viscera.

Median survival is 8 to 9 years.