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Work up of Lymphoma case

September 29, 2020Lab TestsTumor marker

 

  • Lymphoma cases either Non-Hodgkins or Hodgkin’s need the following work up.
  1. Clinical Examination:
    1. Do a careful examination of the lymph node, spleen, liver and etc.
  2. Blood workup:
    1. Total leukocytes (TLC).
    2. Differential leukocyte count (DLC).
    3. Hemoglobin
    4. Erythrocyte sedimentation rate (ESR)
    5. Platelet count.
  3.  Bipedal lymphangiogram.
    1.  This is done for iliac and para-aortic lymph nodes.
  4.  Staging laparotomy:
    1. Laparoscopy can be done for splenectomy, liver biopsy, abdominal lymph nodes, and bone marrow biopsy.
  5.  Biochemical tests are:
    1. Needed are Liver function test (LFT) and lactate dehydrogenase (LDH).
  6.  Ultrasonography.
    1. CT scan and MRI are advised for further work up.
  7. . Advised liver and spleen scan.
    1. 25% positive in nonpalpable spleen by the pathologist.
    2. 50% negative in palpable spleen by the pathologist.
  8. Bone Marrow
    1. 9 to 29% may show in the form of aggregates or diffuse infiltrate.
    2. 25% positive in nonpalpable spleen by the pathologist.
    3. 50% negative in palpable spleen by the pathologist.
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