Intrauterine insemination, IUI (Semen Preparation)
- The husband’s semen is needed which can be directly inserted into the uterine cavity of a wife.
Indication (Candidate for IUI)
- This procedure is useful in a couple where the count is low but there are motile normal sperms.
- Unexplained infertility.
- Low sperm count.
- When the liquefaction of semen is too delayed.
- Decreased sperm mobility.
- A hostile cervical condition, such as cervical mucus that is too thick.
- Cervical scar tissue from past procedures or endometriosis.
- Ejaculation dysfunction.
- Minimal endometriosis.
- Ladies with coital disorders.
Contraindications for Intrauterine insemination
- This is not recommended in the diseases of fallopian tubes.
- Women with endometriosis (moderate to severe).
- Ladies with a history of pelvic infections.
Purpose of Intrauterine insemination
- Placing the prepared sperm directly into the uterine cavity facilitates the process of fertilization.
- IUI is a fertility treatment that uses a catheter to place a number of washed sperm directly into the uterus.
- The goal of IUI is to increase the number of sperm that reach the fallopian tubes and subsequently increase the chance of fertilization.
Advantage of Intrauterine insemination
- It is less invasive and less expensive than in vitro fertilization (IVF).
- Healthy sperms are injected and increase the chances of fertilization.
- The main disadvantage is multiple pregnancies because of the hormones.
- There is a small risk of infection after the IUI.
Procedure of Intrauterine insemination
- A semen sample is collected by masturbation.
- Avoid the use of any chemicals.
- Motile sperms are isolated and the concentration of sperms is increased.
- Special media is needed to isolate the motile sperms.
- A semen sample will be washed by the lab to separate the semen from the seminal fluid.
- Monitor the female for the ovulation who was prepared by giving the hormones.
- A catheter is used to inject the processed sperm directly into the uterus.
- This process maximizes the number of sperm cells that are placed in the uterus.
- Thus increasing the possibility of conception.
- The IUI procedure takes little time and involves minimal discomfort.
Preparation of the women
- An ultrasound will be used to monitor the size of the follicles (follicles develop into eggs).
- The hormone, human Chorionic Gonadotropin (hCG), is administered to stimulate the release of eggs from the follicles.
The success rate of IUI
- Women under the age of 35 usually have higher rates of success than women over the age of 35.
- The average success rate for IUI ranges from 10 to 20% in one cycle.
- The success rate depends upon:
- Primarily on the health of the sperm and the woman’s ovulation status.
- Egg quality and patency of fallopian tubes.