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Intrauterine insemination, IUI (Semen Preparation)

December 24, 2022Fluid analysisLab Tests

Table of Contents

  • Intrauterine insemination
      • Sample
      • Indication (Candidate  for IUI)
      • Contraindications for Intrauterine insemination
      • Purpose of Intrauterine insemination
      • Advantages of Intrauterine insemination
      • Disadvantage
      • The procedure of Intrauterine insemination
      • Preparation of the women
      • The success rate of IUI
      • Questions and answers:

Intrauterine insemination

Sample

  • The husband’s semen is needed, which can be directly inserted into the uterine cavity of a wife.

Indication (Candidate  for IUI)

  1. This procedure is useful in a couple where the count is low, but there are normal motile sperms.
  2. Unexplained infertility.
  3. Low sperm count.
  4. When the liquefaction of semen is too delayed.
  5. Decreased sperm mobility.
  6. A hostile cervical condition, such as cervical mucus, is too thick.
  7. Cervical scar tissue from past procedures or endometriosis.
  8. Ejaculation dysfunction.
  9. Minimal endometriosis.
  10. Ladies with coital disorders.

Contraindications for Intrauterine insemination

  1. This is not recommended for diseases of the fallopian tubes.
  2. Women with endometriosis (moderate to severe).
  3. Ladies with a history of pelvic infections.

Purpose of Intrauterine insemination

  1. Placing the prepared sperm directly into the uterine cavity facilitates the process of fertilization.
  2. IUI is a fertility treatment that uses a catheter to place many washed sperm directly into the uterus.
  3. IUI aims to increase the number of sperm that reach the fallopian tubes and subsequently increase the chance of fertilization.

Advantages of Intrauterine insemination

  1. It is less invasive and less expensive than in vitro fertilization (IVF).
  2. Healthy sperm are injected and increase the chances of fertilization.

Disadvantage

  1. The main disadvantage is multiple pregnancies because of the hormones.
  2. There is a small risk of infection after the IUI.

The procedure of Intrauterine insemination

  1. A semen sample is collected by masturbation.
    1. Avoid the use of any chemicals.
  2. Motile sperms are isolated, and the concentration of sperms is increased.
    1. Special media is needed to isolate the motile sperm.
    2. The lab will wash a semen sample to separate the semen from the seminal fluid.
  3. Monitor the female for ovulation who was prepared by giving the hormones.
    1. A catheter is used to inject the processed sperm directly into the uterus.
  4. This process maximizes the number of sperm cells that are placed in the uterus.
  5. Thus increasing the possibility of conception.
  6. The IUI procedure takes little time and involves minimal discomfort.
Intrauterine insemination

Intrauterine insemination

Preparation of the women

  1. An ultrasound will be used to monitor the size of the follicles (follicles develop into eggs).
  2. The hormone, human Chorionic Gonadotropin (hCG), is administered to stimulate the release of eggs from the follicles.

The success rate of IUI

  1. Women under the age of 35 usually have higher rates of success than women over the age of 35.
  2. The average success rate for IUI ranges from 10 to 20% in one cycle.
  3. The success rate depends upon the following:
    1. Primarily on the health of the sperm and the woman’s ovulation status.
    2. Egg quality and patency of fallopian tubes.

Questions and answers:

Question 1: What is the purpose of IUI?
Show answer
IUI preparation removes the antibodies and gets healthy sperms.
Question 2: Is there any relation with age for IUI?
Show answer
Before the age of 35 years, IUI gives more success.

Possible References Used
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