Viral Hepatitis Markers, Hepatotropic Viruses Summary
Viral hepatitis Markers
Sample
- These tests are done in the serum of the patients.
- Various viral markers for the diagnosis of viral hepatitis.
| Viral Hepatitis | Route of transmission | Antigen / Antibody | Appear (incubation period) | Antigen/Antibody Disappears | Virus structure | Stage of Disease |
|---|---|---|---|---|---|---|
| Hepatitis A | Feco-oral and sexual | HAV-IgM | 4 to 6 weeks | 3 to 4 months | 27-nm RNA virus | Acute infection |
| HAV-IgA | 8 to 12 weeks | 10 years | Previous infection | |||
| Hepatitis B | Parenteral, sexual | HBsAg | 4 to 12 weeks | 1 to 3 months | 42-nm DNA virus | Acute HBV infection |
| HBsAb | 3 to 4 months | 6 to 10 years | Immunity to HBV infection | |||
| HBeAg | 1 to 3 weeks | 6 to 8 weeks | Acute HBV infection | |||
| HBeAg | 4 to 6 weeks | 4 to 6 years | End of acute HBV infection | |||
| HBc IgM | 2 to 12 weeks | 3 to 6 months | Acute HBV infection | |||
| HBcAb-Total | 3 to 12 months | for life | Recovery, or previous infection | |||
| Hepatitis C (HCV) | Parenteral, sexual | HCV-Ag | 2 to 12 weeks | persists | 30 to 60-nm RNA virus | Acute or chronic infection |
| HCV-IgG | 3 to 4 months | 2 years | past infection | |||
| Hepatitis D (HDV) | Feco-oral, sexual, and parenteral ? | HDV- Ag | 1 to 3 days | 3 to 5 days | 36-nm RNA virus | Acute infection |
| HDV-IgM | 10 days | 1 to 3 months | Acute infection | |||
| HDV-Ab total | 2 to 3 days | 7 to 14 months | Chronic HDV infection | |||
| Hepatitis E (HEV) | Feco-oral | Anti-HEV | 15 to 60 days | 32-nm RNA virus | Severe in pregnant females, |