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Tumor Marker:- Part 2 – Summary of Tumor Markers for Various Organs and Monoclonal markers

April 9, 2023Lab TestsTumor marker

Table of Contents

  • Summary of Tumor Markers
    • Monoclonal tumor markers

Summary of Tumor Markers

  • There are specific markers for diagnosing tumors from the various organs in the human body.

Markers For thyroid tumors:

  1. Calcitonin.

Markers For breast tumors:

  1. CA 15-3.
  2. CA 549.
  3. CK-BB.
  4. BRCA-1

Markers For Testicular tumors:

  1. HCG.
  2. AFP.
  3. Calcitonin.

Markers For Prostatic tumors:

  1. PSA.
  2. CA 549.
  3. PAP.

Markers For Bone tumors:

  1. Alkaline phosphatase.

Markers For Lung tumors:

  1. CA 15-3.
  2. CA 549.
  3. CK-BB.

Markers For Liver tumors:

  1. Alkaline phosphatase.
  2. AFP.
  3. CA 19-9.
  4. LDH.

Markers For Gastrointestinal tumors:

  1. CEA.
  2. CA 50.
  3. CA 19-5.
  4. CA 19-9
  5. CA 72-4.

Markers For Colorectal tumors:

  1. CEA.
  2. CA 15-3
  3. CA 19-9.
  4. CA 50.

Markers For Ovarian tumors:

  1. CA 125.
  2. CA 15-3
  3. CA 549.
  4. CK-BB.
  5. CA 72-4.

Markers For Pancreatic tumors:

  1. CEA.
  2. CA 50.
  3. CA 19-9.
  4. CA 15-3.

Monoclonal tumor markers

  1. The first tumor marker was the Bence-Jones protein for multiple myeloma.
  2. α – fetoprotein was discovered in 1963.
  3. CEA was discovered in 1965.
  4. These are defined as the presence of antigens on the tumors, which monoclonal antibodies can identify.
  5. These markers are more specific and sensitive.
Monoclonal antibodies Specific for the tumors
  • Free PSA
  • Prostatic carcinoma
  • CA- 15-3
  • Breast cancer
  • CA- 19-9
  • Pancreatic cancer
  • CA- 125
  • Ovarian cancers
  • CA- 72-4
  • Gastric cancers
  • CA-50
  • Colorectal cancer

Possible References Used
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