Diagnostic value of the Various Enzymes in Diseases

• Enzymes are diagnostic for various diseases and give information for the recovery or prognosis.

A summary of various enzymes in diseases.

Disease	Enzyme	Initial rise	Peak level	Back to normal
Acute Pancreatitis	Lipase	4 to 8 hours	24 hours	8 to 14 days
	Amylase	2 to 12 hours	12 to 72 hours	3 to 4 days
Acute Viral hepatitis	SGOT (AST)	before the onset of jaundice	7 to 12 days	3 to 4 weeks after the onset of jaundice
	SGPT (ALT)	before the onset of jaundice	7 to 12 days after the onset of jaundice	3 to 4 weeks after the onset of jaundice
Acute Hepatobiliary Obstruction	ALK.Phosphatase	immediately		When an obstruction is relieved
	Gamma GT (GGT)	Immediately		when an obstruction is relieved
Acute Myocardial Infarction	SGOT (AST)	6 to 8 hours	18 to 24 hours	4 to 5 days
	LDH	8 to 12 hours	24 to 48 hours	7 to 12 days
	CK-MB	4 to 6 hours	12 to 24 hours	after 48 hours
	Creatine Kinase CK	6 to 8 hours	24 to 36 hours	3 to 4 days
	Myoglobin	2 to 3 hours	6 to 9 hours	24 to 36 hours
	Troponin I	4 to 8 hours	14 to 18 hours	5 to 9 days
	Troponin T	4 to 8 hours	14 to 18 hours	after 14 days
Prostate	Prostatic acid phosphatase	Raised in prostatic carcinoma	A significant increase was seen in metastasis

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