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Congestive Heart Failure, Lab Work up

September 30, 2025Chemical pathologyLab Tests

Table of Contents

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  • Congestive Heart Failure
        • How will you define congestive heart failure?
        • How will you discuss the pathophysiology of Congestive Heart Failure?
      • What is the clinical presentation of heart failure?
        • What are the causes of Left heart failure?
        • What are the causes of Right heart failure?
        • How will you summarize the difference between right-sided and left-sided heart failure?
        • What are the stages of congestive heart failure?
      • Stage A:
      • Stage B:
      • Stage C:
      • Stage D: 
        • How will you do the workup of the patient with heart failure?
      • Lab findings in heart failure:
        • What is the treatment of Congestive heart failure?
      • Questions and answers:

Congestive Heart Failure

How will you define congestive heart failure?

  1. Heart failure is also called congestive heart failure.
    1. This congestive heart failure (biventricular) is used in various conditions, but the best is to restrict this terminology to right heart failure resulting from pre-existing left heart failure.
  2. Biventricular cardiac failure is the most common manifestation of heart failure and can be divided into:
    1. Left cardiac failure.
    2. Right cardiac failure.
  3. Heart failure may be:
    1. Compensated type. The symptoms are stable, and there are no obvious features of fluid retention.
    2. Decompensated type. It is an acute or continuing deterioration of heart failure.
  4. Congestive heart failure is due to damage to the cardiac muscles.
  5. In this condition, the heart cannot pump blood at the rate needed by the body for tissue metabolism.

How will you discuss the pathophysiology of Congestive Heart Failure?

  1. The heart failure may be due to:
    1. Coronary artery disease (CAD). If the coronary arteries become blocked or severely narrowed, the heart becomes starved of oxygen and nutrients.
    2. A heart attack damages the heart muscle, resulting in a scarred area that does not function properly.
    3. Cardiomyopathy. Damage to the heart muscle causes problems other than artery or blood flow problems, such as infections, alcohol, or drug abuse.
    4. High blood pressure leads to overwork of the heart.
    5. Other diseases like valvular diseases, thyroid disease, kidney disease, diabetes, or heart defects present at birth can all cause heart failure.
    6. Heart failure can occur when several diseases or conditions are present at once.
  2. In many pathologic conditions, the onset of heart failure is preceded by cardiac hypertrophy, a compensatory response of the heart.
Congestive Heart Failure: Heart failure

Congestive Heart Failure: Heart failure

What is the clinical presentation of heart failure?

What are the causes of Left heart failure?

  1. Ischemic disease is the most common cause.
  2. There is systemic hypertension, chronic or malignant.
  3. There may be diseases affecting the aortic or mitral valves.
  4. There may be cardiomyopathy.

What are the causes of Right heart failure?

  1. This syndrome is seen in various conditions.
  2. It is seen in left heart failure.
  3. This may be due to chronic obstructive pulmonary disease (COPD) or cor pulmonale.
  4. The patient may have tricuspid valve disease.
  5. There may be pulmonary valve disease.
  6. There may be isolated right ventricular cardiomyopathy.
  7. There may be atrial or ventricular septal defects.
  8. There may be mitral valve disease with pulmonary hypertension.
Congestive Heart Failure: Causes of Heart failure

Congestive Heart Failure: Causes of Heart Failure

  1. Congestive heart failure is the most common cause of transudative pleural effusion.
  2. In treated cases, transudate may change into exudate.
  3. Effusion due to congestive heart failure is more on the right side.

How will you summarize the difference between right-sided and left-sided heart failure?

Clinical presentations Right-sided heart failure Left-sided heart failure
  • Mechanism
  1. Can not pump blood to the lungs
  2. The right ventricle is weak
  1. The left side of the heart can not pump blood to various parts
  2. Problem with the left ventricle
  • Blood  problem to
  • Systemic circulation
  • Lungs (pulmonary circulation)
  • Clinical presentation
  • Edema of the feet
  1. Dyspnoea
  2. Fatigue and weakness
  3. Difficult breathing while lying in bed (orthopnoea)
  4. Cough with frothy, pink sputum
  5. Paroxysmal nocturnal dyspnoea

What are the stages of congestive heart failure?

  • Heart failure, according to the American College of Cardiology and American Heart Association, is divided into four stages:

Stage A:

  1. These patients in stage A are those groups with the following illnesses and risk of developing heart failure, but have no signs or symptoms of failure.
    1. Patients with diabetes.
    2. With H/O blood pressure.
    3. Patient with H/O coronary disease.
    4. Patient with metabolic syndrome.
    5. Excessive use of alcohol.
    6. With H/o cardiac toxic drug therapy.
    7. H/O rheumatic fever.
    8. Patients with family H/O of cardiomyopathy.

Stage B:

  1. These patients have heart disease but no symptoms.
    1. Patients with H/O heart attack.
    2. Patient with low ejection fraction.
    3. Valvular diseases without symptoms.

Stage C:

  1. This group has heart disease and symptoms.
  2. These patients have shortness of breath.
  3. Decreased stamina or decreased ability for exercise.
  4. Easy fatigability.

Stage D: 

  1. This group has advanced heart disease and needs aggressive medical treatment.
  2. These patients have systolic heart failure and all signs and symptoms of heart failure.

How will you do the workup of the patient with heart failure?

  1. Electrocardiogram (ECG).
  2. X-Ray chest.
  3. Blood test for:
    1. Electrolytes, Na. K, Mg.
    2. Cardiac enzymes.
    3. Thyroid function test.
  4. Kidney function test.
  5. Stress test.
  6. MRI
  7. Cardiac catheterization or angiography.

Lab findings in heart failure:

Serum 
  • Sodium
  • Normal or decreased
  • Potassium
  • Normal
  • Bicarbonate
  • Normal
  • Chloride
  • Decreased
  • Volume
  • Increased
Urine 
  • Sodium
  • Decreased
  • Potassium
  • Normal
  • pH
  • Normal
  • Volume
  • Decreased

What is the treatment of Congestive heart failure?

  1. To prevent heart failure, advise the patient:
    1. Stop smoking.
    2. Stop alcohol intake.
    3. Stop the use of harmful drugs (drug abuse).
  2. Treat hypertension.
  3. Treat hypercholesterolemia.
  4. Give adequate treatment after AMI.
  5. Treatment of chronic heart failure target:
    1. Relieve the symptoms.
  6. Bed rest is helpful in the early days of congestive heart failure.
  7. Diuretics reduce the load on the heart.
  8. Bed rest may lead to deep vein thrombosis, so administer heparin and provide elastic stockings.
  9. Start exercising slowly for 20 to 30 minutes, walking 2 to 3 times a week.
  10. Can start cycling for 20 minutes at 70% to 80% of peak heart rate five times per week.
  11. Modify the diet.

Questions and answers:

Question 1: What is the classification by the American College of Cardiology?
Show answer
American College of Cardiology divides heart failure into four stages?
Question 2: What is saerum K+ and serum Na+ in heart failure?
Show answer
In heart failure K+ is normal and Na+ may be normal or decreased.

Possible References Used
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