Childhood Lymphoma

These lymphomas  are never nodular.

These are more aggressive lymphomas.

Majority become leukemic.

Burkitt’s Lymphoma

• Age: Usually these lymphoma starts at 7 years.

• Site: Common site is Jaws (mandible and maxilla).

• EBV is associated in 98% of the cases.

• EBV antibodies are seen in 100% of the cases.

• Child when develop after the age of 13 years have poor prognosis then the younger patients.

Non-Burkitt’s Lymphoma

• This is seen in 60% of the childhood lymphomas.

• Age: Median age is 34 years. While it can be seen from 10 to 70 years of age.

• Sex: male to female ratio is same.

• Sites: This can be seen in lymph nodes, bone marrow, central nervous system, gastrointestinal system, liver and ovaries.

• Histology: There is infiltrate of pleomorphic cells.

• Majority are small non-cleaved cells.

• There is less repose to treatment.

• These lymphomas are treated aggressively like large cell lymphoma.