Porphyrias

This is a group of metabolic disorder that results from the disturbance in porphyrin metabolism.

1. There is increased formation and excretion of porphyrins and its precursors.
2. Acute intermittent porphyria is being inherited  (autosomal dominant) form that will lead to:
   1. Abdominal pain.
   2. Neurological disturbance.
3. These can be diagnosed by the measurement of porphyrins and porphyrin intermediates.